6umx: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6umx is ON HOLD
+==Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015==
+<StructureSection load='6umx' size='340' side='right'caption='[[6umx]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6umx]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UMX FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6umx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6umx OCA], [http://pdbe.org/6umx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6umx RCSB], [http://www.ebi.ac.uk/pdbsum/6umx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6umx ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Myostatin-related muscle hypertrophy. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Acts specifically as a negative regulator of skeletal muscle growth.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Bostion, C J]]
+[[Category: Capili, A D]]
+[[Category: Carven, G J]]
+[[Category: Dagbay, K B]]
+[[Category: Faucette, R R]]
+[[Category: Jackson, J W]]
+[[Category: Lin, S C]]
+[[Category: Nicholls, S B]]
+[[Category: Nikiforov, A]]
+[[Category: Streich, F C]]
+[[Category: Treece, E]]
+[[Category: Antibody]]
+[[Category: Fab]]
+[[Category: Gdf8]]
+[[Category: Muscle wasting disease]]
+[[Category: Myostatin]]
+[[Category: Signaling protein-immune system complex]]
+[[Category: Transforming growth factor beta]]