6qop: Difference between revisions

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'''Unreleased structure'''


The entry 6qop is ON HOLD
==Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 19 (5-fluoroquinazolin-4-ol)==
 
<StructureSection load='6qop' size='340' side='right'caption='[[6qop]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
Authors: Thomas, S.E., Whitehouse, A.J., Coyne, A.G., Abell, C., Mendes, V., Blundell, T.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6qop]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QOP FirstGlance]. <br>
Description: Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 19 (5-fluoroquinazolin-4-ol)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JBQ:5-fluoranyl-3,4-dihydroquinazolin-4-ol'>JBQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nvr|6nvr]]</td></tr>
[[Category: Blundell, T.L]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qop OCA], [http://pdbe.org/6qop PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qop RCSB], [http://www.ebi.ac.uk/pdbsum/6qop PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qop ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/B1MDI3_MYCA9 B1MDI3_MYCA9]] Specifically methylates guanosine-37 in various tRNAs.[HAMAP-Rule:MF_00605][RuleBase:RU003464][SAAS:SAAS00040552]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Abell, C]]
[[Category: Blundell, T L]]
[[Category: Coyne, A G]]
[[Category: Mendes, V]]
[[Category: Mendes, V]]
[[Category: Thomas, S.E]]
[[Category: Thomas, S E]]
[[Category: Abell, C]]
[[Category: Whitehouse, A J]]
[[Category: Whitehouse, A.J]]
[[Category: Spout methyltransferase]]
[[Category: Coyne, A.G]]
[[Category: Transferase]]
[[Category: Trmd]]
[[Category: Trna methyltransferase]]

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