Flaps Morph for HIV Protease: Difference between revisions

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<center>{{Template:Button_Toggle_Animation2}}</center>
<center>{{Template:Button_Toggle_Animation2}}</center>
''Click the Toggle Animation Button above to '''start''' these animations if needed.''
''Click the Toggle Animation Button above to '''start''' these animations if needed.''
* <scene name='83/836583/Morph/7'>Morph of ribbon/cartoon with</scene> <font color="magenta">'''flap glycines in magenta'''</font> (Gly 40, 48, 49, 51, 52).
* <scene name='83/836583/Morph/11'>Morph of ribbon/cartoon with</scene> <font color="magenta">'''flap glycines in magenta'''</font> (Gly 40, 48, 49, 51, 52).
* <scene name='83/836583/Morph/3'>Morph of ribbon/cartoon with flaps highlighted</scene> in <font color="orange">'''orange'''</font>. (Flaps: residues 42-58.)
* <scene name='83/836583/Morph/9'>Morph of ribbon/cartoon with flaps highlighted</scene> in <font color="orange">'''orange'''</font>. (Flaps: residues 42-58.)
* <scene name='83/836583/Morph/5'>Morph of spacefilling rendition</scene> with flaps highlighted in <font color="orange">'''orange'''</font>.
* <scene name='83/836583/Morph/10'>Morph of spacefilling rendition</scene> with flaps highlighted in <font color="orange">'''orange'''</font>.


In the case of mutant [[1tw7]], about 100 water molecules (not shown) reside in the active site, forming a hydrogen-bonded scaffold holding the flaps open<ref name="wide-open" />.  
In the case of mutant [[1tw7]], about 100 water molecules (not shown) reside in the active site, forming a hydrogen-bonded scaffold holding the flaps open<ref name="wide-open" />.  

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Eric Martz