Flaps Morph for HIV Protease: Difference between revisions
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Here is shown a morph between a closed HIV protease and a "wide open" protease (<scene name='83/836583/Morph/1'>restore initial scene</scene>). (Note that "wide open" is not "fully open" -- see above.) | Here is shown a morph between a closed HIV protease and a "wide open" protease (<scene name='83/836583/Morph/1'>restore initial scene</scene>). (Note that "wide open" is not "fully open" -- see above.) | ||
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In the case of mutant [[1tw7]], about 100 water molecules reside in the active site, forming a hydrogen-bonded scaffold holding the flaps open<ref name="wide-open" />. | In the case of mutant [[1tw7]], about 100 water molecules reside in the active site, forming a hydrogen-bonded scaffold holding the flaps open<ref name="wide-open" />. | ||