Thioredoxin: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The <scene name='43/430885/Cv/4'>active site motif Cys-Gly-Pro-Cys</scene> is involved in the reduction of disulfide bonds in proteins<ref>PMID:8805557</ref> | The <scene name='43/430885/Cv/4'>active site motif Cys-Gly-Pro-Cys</scene> is involved in the reduction of disulfide bonds in proteins<ref>PMID:8805557</ref> | ||
== 3D Structures of Thioredoxin == | |||
[[Thioredoxin 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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*Thioredoxin | *Thioredoxin | ||
**[[3e3e]], [[2hsh]], [[1aiu]], [[1erv]], [[1erw]], [[3m9j]], [[3m9k]], [[4oo4]] – hTrx (mutant) | **[[1auc]], [[1ert]], [[1eru]] - hTrx - human<br /> | ||
**[[3e3e]], [[2hsh]], [[1aiu]], [[1erv]], [[1erw]], [[3m9j]], [[3m9k]], [[4oo4]] – hTrx (mutant) <br /> | |||
**[[2hxk]], [[2ifq]], [[2iiy]] – hTrx S-nitroso<br /> | **[[2hxk]], [[2ifq]], [[2iiy]] – hTrx S-nitroso<br /> | ||
**[[4oo5]] - hTrx S-nitroso (mutant)<br /> | **[[4oo5]] - hTrx S-nitroso (mutant)<br /> | ||
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**[[5dqy]] – hTrx oxidized<br /> | **[[5dqy]] – hTrx oxidized<br /> | ||
**[[1trs]], [[1tru]], [[1trv]], [[1trw]], [[3trx]], [[4trx]] - hTrx - NMR<br /> | **[[1trs]], [[1tru]], [[1trv]], [[1trw]], [[3trx]], [[4trx]] - hTrx - NMR<br /> | ||
**[[1xw9]], [[1xwa]], [[1xwb]], [[1xwc]] – Trx – ''Drosophila melanogaster''<br /> | |||
**[[1gl8]] – sTrx – spinach - NMR<br /> | |||
**[[3hxs]] – BfTrx fragment – ''Bacteroides fragilis''<br /> | **[[3hxs]] – BfTrx fragment – ''Bacteroides fragilis''<br /> | ||
**[[3hyp]] - BfrxI fragment (mutant)<br /> | **[[3hyp]] - BfrxI fragment (mutant)<br /> | ||
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**[[2f51]] – Trx – ''Trichomonas vaginalis''<br /> | **[[2f51]] – Trx – ''Trichomonas vaginalis''<br /> | ||
**[[1t00]] – Trx – ''Streptomyces coelicolor''<br /> | **[[1t00]] – Trx – ''Streptomyces coelicolor''<br /> | ||
**[[1rqm]], [[1nsw]], [[1nw2]] – Trx (mutant) – ''Alicyclobacillus acidocaldarius'' – NMR<br /> | **[[1rqm]], [[1nsw]], [[1nw2]] – Trx (mutant) – ''Alicyclobacillus acidocaldarius'' – NMR<br /> | ||
**[[1syr]] – PfTrx – ''Plasmodium falciparum''<br /> | **[[1syr]] – PfTrx – ''Plasmodium falciparum''<br /> | ||
**[[2mmn]], [[2mmo]] - PfTrx - NMR<br /> | **[[2mmn]], [[2mmo]] - PfTrx - NMR<br /> | ||
**[[1r26]] – Trx – ''Trypanosoma brucei brucei''<br /> | **[[1r26]] – Trx – ''Trypanosoma brucei brucei''<br /> | ||
**[[1fo5]] – Trx – ''Methanocaldococcus janaschii'' – NMR<br /> | **[[1fo5]] – Trx – ''Methanocaldococcus janaschii'' – NMR<br /> | ||
**[[1quw]] – Trx – ''Bacillus acidocaldarius'' – NMR<br /> | **[[1quw]] – Trx – ''Bacillus acidocaldarius'' – NMR<br /> | ||
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*Thioredoxin 1 | *Thioredoxin 1 | ||
**[[1oaz]] – Trx-1+immunoglobulin E – rat<br /> | |||
**[[3f3q]], [[2i9h]] – yTrx-1 – yeast<br /> | **[[3f3q]], [[2i9h]] – yTrx-1 – yeast<br /> | ||
**[[3f3r]] – yTrx-1 (mutant)<br /> | **[[3f3r]] – yTrx-1 (mutant)<br /> | ||
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**[[1tk5]] - EpTrx-1+DNA primer+DNA template+DNA polymerase+8-oxo-guanosine<br /> | **[[1tk5]] - EpTrx-1+DNA primer+DNA template+DNA polymerase+8-oxo-guanosine<br /> | ||
**[[2bto]] – Trx-1+tubulin btuba – ''Prosthecobacter dejongeii''<br /> | **[[2bto]] – Trx-1+tubulin btuba – ''Prosthecobacter dejongeii''<br /> | ||
**[[3tco]] - SsTrx-1 fragment – ''Sulfolobus solfataricus''<br /> | **[[3tco]] - SsTrx-1 fragment – ''Sulfolobus solfataricus''<br /> | ||
**[[4j57]], [[4j56]] – PfTrx-1 + Trx reductase (mutant)<br /> | **[[4j57]], [[4j56]] – PfTrx-1 + Trx reductase (mutant)<br /> | ||
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*Thioredoxin F | *Thioredoxin F | ||
**[[1f9m]] – sTrx F <br /> | |||
**[[1faa]] - sTrx F (mutant)<br /> | |||
**[[2pu9]] – SsTrx F+ferredoxin thioredoxin reductase – Synechocystis<br /> | **[[2pu9]] – SsTrx F+ferredoxin thioredoxin reductase – Synechocystis<br /> | ||
**[[2pvo]] - SsTrx F+ferredoxin thioredoxin reductase+ferredoxin 1<br /> | **[[2pvo]] - SsTrx F+ferredoxin thioredoxin reductase+ferredoxin 1<br /> | ||
*Thioredoxin H | *Thioredoxin H | ||
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*Thioredoxin M | *Thioredoxin M | ||
**[[1fb0]], [[1fb6]] - sTrx M<br /> | |||
**[[2puk]] - SsTrx M+ferredoxin thioredoxin reductase<br /> | **[[2puk]] - SsTrx M+ferredoxin thioredoxin reductase<br /> | ||
**[[1dby]] – CrTrx M – NMR<br /> | **[[1dby]] – CrTrx M – NMR<br /> | ||
}} | }} | ||