Thiol:disulfide interchange protein: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
DsbC active site contains a <scene name='70/705687/Cv/2'>CXXC motif</scene> which modulates the disulfide isomerization and protein folding in the bacterial periplasmic space<ref>PMID:11208797</ref><ref>PMID:11208797</ref>.
DsbC active site contains a <scene name='70/705687/Cv/2'>CXXC motif</scene> which modulates the disulfide isomerization and protein folding in the bacterial periplasmic space<ref>PMID:11208797</ref><ref>PMID:11208797</ref>.
== 3D Structures of thiol:disulfide interchange protein ==
[[Thiol:disulfide interchange protein 3D structures]]
</StructureSection>
</StructureSection>


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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
*Thiol:disulfide interchange protein (DsbA) see [[Protein disulfide oxidoreductase]]
* Thiol:disulfide interchange protein (DsbB)
**[[3e9j], [[2zup]]] – EcDsbB (mutant) + DsbA (mutant) - ''Escherichal coli''  <BR />
**[[2leg]]] – EcDsbB (mutant) + DsbA (mutant) - NMR<BR />
**[[2hi7]]] – EcDsbB (mutant) + DsbA (mutant) + ubiquinone <BR />
**[[2zuq]] – EcDsbB (mutant) + antibody<BR />


*Thiol:disulfide interchange protein (DsbC)
*Thiol:disulfide interchange protein (DsbC)


**[[1eej]], [[1tjd]] – EcDsbC – ''Escherichal coli'' <BR />
**[[1eej]], [[1tjd]] – EcDsbC <BR />
**[[1g0t]], [[1jzo]] – EcDsbC (mutant) <BR />
**[[1g0t]], [[1jzo]] – EcDsbC (mutant) <BR />
**[[2iyj]] – EcDsbC N terminal<BR />
**[[2iyj]] – EcDsbC N terminal<BR />
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**[[2b1l]], [[2g0f]] – EcDsbE (mutant) <BR />
**[[2b1l]], [[2g0f]] – EcDsbE (mutant) <BR />
**[[3kh7]], [[3kh9]] – DsbE soluble domain – ''Pseudomonas aeruginosa''<BR />
**[[3kh7]], [[3kh9]] – DsbE soluble domain – ''Pseudomonas aeruginosa''<BR />
*Thiol:disulfide interchange protein (DsbF)
**[[3ios]] – DsbF – ''Mycobacterium tuberculosis'' <BR />


*Thiol:disulfide interchange protein (DsbG)
*Thiol:disulfide interchange protein (DsbG)

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Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman