6efa: Difference between revisions

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'''Unreleased structure'''


The entry 6efa is ON HOLD  until Paper Publication
==GspB Siglec + Unique domains==
 
<StructureSection load='6efa' size='340' side='right'caption='[[6efa]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors: Iverson, T.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6efa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EFA FirstGlance]. <br>
Description: GspB Siglec + Unique domains
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ef7|6ef7]], [[5iuc|5iuc]], [[6ef9|6ef9]], [[6efb|6efb]], [[6efc|6efc]], [[6efd|6efd]], [[6eff|6eff]], [[6efi|6efi]]</td></tr>
[[Category: Iverson, T.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6efa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6efa OCA], [http://pdbe.org/6efa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6efa RCSB], [http://www.ebi.ac.uk/pdbsum/6efa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6efa ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GSPB_STRGN GSPB_STRGN]] Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA.<ref>PMID:21765814</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Iverson, T M]]
[[Category: Lectin]]
[[Category: Sugar binding protein]]

Revision as of 09:16, 19 February 2020

GspB Siglec + Unique domainsGspB Siglec + Unique domains

Structural highlights

6efa is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GSPB_STRGN] Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA.[1]

References

  1. ↑ Pyburn TM, Bensing BA, Xiong YQ, Melancon BJ, Tomasiak TM, Ward NJ, Yankovskaya V, Oliver KM, Cecchini G, Sulikowski GA, Tyska MJ, Sullam PM, Iverson TM. A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors. PLoS Pathog. 2011 Jul;7(7):e1002112. Epub 2011 Jul 7. PMID:21765814 doi:10.1371/journal.ppat.1002112

6efa, resolution 1.60Å

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OCA
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