Sandbox Reserved 1105: Difference between revisions
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=== Structure === | === Structure === | ||
<Structure load='1dvq' size='350' frame='true' align='right' caption='Crystal Structure of human transthyretin (TTR) from homo sapiens gene in Escherichia coli | <Structure load='1dvq' size='350' frame='true' align='right' caption='Crystal Structure of human transthyretin (TTR) from homo sapiens gene in Escherichia coli, resolution 2Å (PDB entry : [[1dvq]])' scene='3D structure of human transthyretin' /> | ||
Human TTR is a 54 kDa homo-tetramer, described as a dimer of dimer, rich in β-sheet. It is composed of 127 amino acids assembled around the central channel of the protein, resulting in a 222 symmetry protein. This tetramer contains a channel divided into two symmetry-related L-T4-binding sites. | Human TTR is a 54 kDa homo-tetramer, described as a dimer of dimer, rich in β-sheet. It is composed of 127 amino acids assembled around the central channel of the protein, resulting in a 222 symmetry protein. This tetramer contains a channel divided into two symmetry-related L-T4-binding sites. | ||
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=== Dibenzofuran-4,6-dicarboxylic acid === | === Dibenzofuran-4,6-dicarboxylic acid === | ||
<Structure load='1dvu' size='340' frame='true' align='right' caption='Crystal Structure of human transthyretin in complex with dibenzofuran-4,6-dicarboxylic acid from homo sapiens gene in Escherichia coli | <Structure load='1dvu' size='340' frame='true' align='right' caption='Crystal Structure of human transthyretin in complex with dibenzofuran-4,6-dicarboxylic acid from homo sapiens gene in Escherichia coli, resolution 2.05Å (PDB entry : [[1dvu]]) ' scene='Insert optional scene name here' /> | ||