6pof: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6pof is ON HOLD  until Paper Publication
+==Structure of human ATP citrate lyase==
+<StructureSection load='6pof' size='340' side='right'caption='[[6pof]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6pof]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6POF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6POF FirstGlance]. <br>
-Description:
+</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_citrate_synthase ATP citrate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.8 2.3.3.8] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pof OCA], [http://pdbe.org/6pof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pof RCSB], [http://www.ebi.ac.uk/pdbsum/6pof PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pof ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN]] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: ATP citrate synthase]]
+[[Category: Large Structures]]
+[[Category: Ronen, M]]
+[[Category: Xuepeng, W]]
+[[Category: Apo]]
+[[Category: Lyase]]