6jjs: Difference between revisions

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-'''Unreleased structure'''
-The entry 6jjs is ON HOLD  until Feb 26 2021
+==Crystal structure of an enzyme from Penicillium herquei in condition2==
+<StructureSection load='6jjs' size='340' side='right'caption='[[6jjs]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6jjs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JJS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JJS FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jjs OCA], [http://pdbe.org/6jjs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jjs RCSB], [http://www.ebi.ac.uk/pdbsum/6jjs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jjs ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Hydroalkoxylation is a useful and efficient reaction which generates C-O bond and produces cyclic ethers, the common structural elements of natural products. The dedicative enzyme which can catalyze enantioselective hydroalkoxylation named PhnH was recently identified in the herqueinone biosynthetic gene from Penicillium herquei. It catalyzes addition of a phenol to the terminal olefin on substrate to produce a dihydrobenzofuran. Here, the crystal structure of PhnH is reported and the putative substrate-binding pocket is illustrated. Through docking experiment, possible substrate-binding poses are displayed and the catalytic mechanism is therefore proposed. Our findings form the basis for further studies of enantioselective hydroalkoxylation enzymes.
-Authors: Fen, Y., Huang, J.W., Liu, W.D., Chen, C.C., Guo, R.T.
+Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.,Feng Y, Yu X, Huang JW, Liu W, Li Q, Hu Y, Yang Y, Chen Y, Jin J, Li H, Chen CC, Guo RT Biochem Biophys Res Commun. 2019 Aug 27;516(3):801-805. doi:, 10.1016/j.bbrc.2019.06.100. Epub 2019 Jun 27. PMID:31256936<ref>PMID:31256936</ref>
-Description: Crystal structure of an enzyme from Penicillium herquei in condition2
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Huang, J.W]]
+<div class="pdbe-citations 6jjs" style="background-color:#fffaf0;"></div>
-[[Category: Liu, W.D]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Chen, C C]]
 [[Category: Fen, Y]]
-[[Category: Chen, C.C]]
+[[Category: Guo, R T]]
-[[Category: Guo, R.T]]
+[[Category: Huang, J W]]
+[[Category: Liu, W D]]
+[[Category: Prenyltransferase]]
+[[Category: Transferase]]