6cvw: Difference between revisions
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==Crystal structure of HCV NS3/4A WT protease in complex with AJ-52 (MK-5172 linear analogue)== | ==Crystal structure of HCV NS3/4A WT protease in complex with AJ-52 (MK-5172 linear analogue)== | ||
<StructureSection load='6cvw' size='340' side='right' caption='[[6cvw]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='6cvw' size='340' side='right'caption='[[6cvw]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6cvw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CVW FirstGlance]. <br> | <table><tr><td colspan='2'>[[6cvw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CVW FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FH1:N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-4-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-L-prolinamide'>FH1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FH1:N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-4-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-L-prolinamide'>FH1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cvw OCA], [http://pdbe.org/6cvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cvw RCSB], [http://www.ebi.ac.uk/pdbsum/6cvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cvw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cvw OCA], [http://pdbe.org/6cvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cvw RCSB], [http://www.ebi.ac.uk/pdbsum/6cvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cvw ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Matthew, A N]] | [[Category: Matthew, A N]] | ||
[[Category: Schiffer, C A]] | [[Category: Schiffer, C A]] | ||