5irx: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc== | ==Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc== | ||
<StructureSection load='5irx' size='340' side='right' caption='[[5irx]], [[Resolution|resolution]] 2.95Å' scene=''> | <StructureSection load='5irx' size='340' side='right'caption='[[5irx]], [[Resolution|resolution]] 2.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5irx]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IRX FirstGlance]. <br> | <table><tr><td colspan='2'>[[5irx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Cyrsc Cyrsc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IRX FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6EU:RESINIFERATOXIN'>6EU</scene>, <scene name='pdbligand=6O8:(4R,7S)-4-HYDROXY-N,N,N-TRIMETHYL-4,9-DIOXO-7-[(PENTANOYLOXY)METHYL]-3,5,8-TRIOXA-4LAMBDA~5~-PHOSPHATETRADECAN-1-AMINIUM'>6O8</scene>, <scene name='pdbligand=6O9:(2S)-2-(ACETYLOXY)-3-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}PROPYL+PENTANOATE'>6O9</scene>, <scene name='pdbligand=6OE:(2S)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(HEXANOYLOXY)PROPYL+HEXANOATE'>6OE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6EU:RESINIFERATOXIN'>6EU</scene>, <scene name='pdbligand=6O8:(4R,7S)-4-HYDROXY-N,N,N-TRIMETHYL-4,9-DIOXO-7-[(PENTANOYLOXY)METHYL]-3,5,8-TRIOXA-4LAMBDA~5~-PHOSPHATETRADECAN-1-AMINIUM'>6O8</scene>, <scene name='pdbligand=6O9:(2S)-2-(ACETYLOXY)-3-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}PROPYL+PENTANOATE'>6O9</scene>, <scene name='pdbligand=6OE:(2S)-3-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-2-(HEXANOYLOXY)PROPYL+HEXANOATE'>6OE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5irz|5irz]], [[5is0|5is0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5irz|5irz]], [[5is0|5is0]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Trpv1, Vr1, Vr1l ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5irx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5irx OCA], [http://pdbe.org/5irx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5irx RCSB], [http://www.ebi.ac.uk/pdbsum/5irx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5irx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5irx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5irx OCA], [http://pdbe.org/5irx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5irx RCSB], [http://www.ebi.ac.uk/pdbsum/5irx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5irx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 23: | Line 24: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Buffalo rat]] | |||
[[Category: Cyrsc]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao, E]] | [[Category: Cao, E]] | ||
[[Category: Cheng, Y]] | [[Category: Cheng, Y]] | ||