Rho guanine nucleotide exchange factor: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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== Disease == | == Disease == | ||
Increased GEF activity is involved in cancer cell proliferation by affecting Rho GTPases <ref>PMID:24037532</ref>. | Increased GEF activity is involved in cancer cell proliferation by affecting Rho GTPases <ref>PMID:24037532</ref>. | ||
== 3D Structures of Rho guanine nucleotide exchange factor == | |||
[[Rho guanine nucleotide exchange factor 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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*Rho guanine nucleotide exchange factor 8 (PRONE8) | *Rho guanine nucleotide exchange factor 8 (PRONE8) | ||
**[[3eo2]] – hGEF residues 161-373 <br /> | |||
**[[4xh9]] – hGEF DH/PH domain + transforming protein RhoA <br /> | |||
**[[2ntx]] – AtGEF PRONE domain – ''Arabidopasis thaliana''<br /> | **[[2ntx]] – AtGEF PRONE domain – ''Arabidopasis thaliana''<br /> | ||
**[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br /> | **[[2wbl]] – AtGEF PRONE domain + GTPase ROP7 <br /> | ||
**[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br /> | **[[2nty]] – AtGEF PRONE domain + GTPase ROP4 + GDP <br /> | ||
*Rho guanine nucleotide exchange factor 9 (collybistin) | *Rho guanine nucleotide exchange factor 9 (collybistin) | ||