Anthrax edema factor: Difference between revisions

No edit summary
No edit summary
Line 3: Line 3:
== Function ==
== Function ==


'''Anthrax edema factor''' (EF) or '''calmodulin-sensitive adenylate cyclase''' is an enzyme which is part of the ''Bacillus anthracis'' anthrax toxin.  The full anthrax toxin is composed of a cell-binding protein ([[Anthrax protective antigen|protective antigen]]), [[Anthrax Lethal Factor|lethal factor]] and EF. The EF is a calcium- and calmodulin-dependent adenylate cyclase.  The binding of calmodulin to EF changes it from its non-active form to the active one.<ref>PMID:15680766</ref>
'''Anthrax edema factor''' (EF) or '''calmodulin-sensitive adenylate cyclase''' is an enzyme which is part of the ''Bacillus anthracis'' anthrax toxin.  The full anthrax toxin is composed of a cell-binding protein ([[Anthrax protective antigen|protective antigen]]), [[Anthrax Lethal Factor|lethal factor]] and EF. The EF is a calcium- and calmodulin-dependent adenylate cyclase.  The binding of calmodulin to EF changes it from its non-active form to the active one.<ref>PMID:15680766</ref> See also [[Toxins]].


== Disease ==
== Disease ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky