Phosphoglucose isomerase: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='' size='350' side='right' scene='48/481605/Cv/2' caption='Rabbit phosphoglucose isomerase dimer complex with fructose-6-phosphate, [[1hox]]'> | <StructureSection load='' size='350' side='right' scene='48/481605/Cv/2' caption='Rabbit phosphoglucose isomerase dimer complex with fructose-6-phosphate, [[1hox]]'> | ||
== Function == | == Function == | ||
'''Phosphoglucose isomerase''' (PGI) or '''glucose-6-phosphate isomerase''' catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate<ref>PMID:25811607</ref>. The encoded protein is also referred to as '''autocrine motility factor''' (AMF) based on an additional function as a '''tumor-secreted cytokine''' and '''angiogenic factor'''. PGI is part of the glycolysis cycle. For more details see [[Phosphoglucoisomerase]]. | '''Phosphoglucose isomerase''' (PGI) or '''glucose-6-phosphate isomerase''' catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate<ref>PMID:25811607</ref>. The encoded protein is also referred to as '''autocrine motility factor''' (AMF) based on an additional function as a '''tumor-secreted cytokine''' and '''angiogenic factor''' (see [[Growth factors]]). PGI is part of the glycolysis cycle. For more details see [[Phosphoglucoisomerase]]. | ||
== Disease == | == Disease == | ||