190d: Difference between revisions

Revision as of 09:34, 2 May 2008

CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)

OverviewOverview

The crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested.

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764 Page seeded by OCA on Fri May 2 09:34:52 2008

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OCA

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 [[Image:190d.gif|left|200px]]
- {{Structure
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-}}
 '''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)'''
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 ==About this Structure==
-D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA].
+Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA].
 ==Reference==
 Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7947764 7947764]
-[[Category: Protein complex]]
 [[Category: Cai, L.]]
 [[Category: Chen, L.]]
 [[Category: Rich, A.]]
 [[Category: Zhang, X.]]
-[[Category: base intercalated]]
+[[Category: Base intercalated]]
-[[Category: mismatched]]
+[[Category: Mismatched]]
-[[Category: parallel-stranded tetraplex]]
+[[Category: Parallel-stranded tetraplex]]
-[[Category: quadruple helix]]
+[[Category: Quadruple helix]]
-[[Category: u-dna]]
+[[Category: U-dna]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 09:34:52 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:29:47 2008''