|
|
| Line 1: |
Line 1: |
| <StructureSection load='' size='350' side='right' caption='Structure of phosphocarrier protein HPr (PDB entry [[1fu0]])' scene='57/570591/Cv/1'> | | <StructureSection load='' size='350' side='right' caption='Structure of phosphocarrier protein HPr (PDB entry [[1fu0]])' scene='57/570591/Cv/1'> |
| | __TOC__ |
| == Function == | | == Function == |
| '''Phosphocarrier protein HPr''' (HPr) is a component of the sugar phosphotransferase system. The system catalyses the phosphorylation of sugars during their translocation across cell membrane. A phosphoryl group is transferred from phosphoenolpyruvate via several enzymes (EI, EII) to HPr<ref>PMID:8246840</ref>. A conserved histidine in the N terminal of HPr is the acceptor of the phosphate. In Gram-positive bacteria HPr there is a conserved serine which is phosphorylated. | | '''Phosphocarrier protein HPr''' (HPr) is a component of the sugar phosphotransferase system. The system catalyses the phosphorylation of sugars during their translocation across cell membrane. A phosphoryl group is transferred from phosphoenolpyruvate via several enzymes (EI, EII) to HPr<ref>PMID:8246840</ref>. A conserved histidine in the N terminal of HPr is the acceptor of the phosphate. In Gram-positive bacteria HPr there is a conserved serine which is phosphorylated. |
| Line 15: |
Line 16: |
| </StructureSection> | | </StructureSection> |
|
| |
|
| ==3D structures of phosphocarrier protein HPr==
| |
|
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| *Phosphocarrier protein HPr
| |
|
| |
| **[[2hpr]] - BsHPr (mutant) – ''Bacillus subtilis'' <br />
| |
| **[[2hid]] - BsHPr (mutant) – NMR <br />
| |
| **[[1jem]] - BsHPr (mutant) with phosphohistidine – NMR <br />
| |
| **[[1sph]] – BsHPr <br />
| |
| **[[1poh]] – EcHPr – ''Escherichia coli'' <br />
| |
| **[[1opd]], [[1cm2]], [[1cm3]], [[3ccd]] - EcHPr (mutant) <br />
| |
| **[[1hdn]] - EcHPr – NMR <br />
| |
| **[[1pfh]] - EcHPr with phosphohistidine – NMR <br />
| |
| **[[1ptf]] - EfHPr – ''Enterococcus faecalis'' <br />
| |
| **[[1qfr]] - EfHPr – NMR <br />
| |
| **[[1fu0]] - EfHPr with phosphoserine <br />
| |
| **[[1pch]] – HPr – ''Mycoplasma capricolum''<br />
| |
| **[[1qr5]] - ScHPr – ''Staphylococcus carnosus'' - NMR <br />
| |
| **[[1txe]] - ScHPr (mutant) – NMR <br />
| |
| **[[1ka5]] - HPr – ''Staphylococcus aureus'' - NMR <br />
| |
| **[[1y4y]] – GsHPr – ''Geobacillus stearothermophilus''<br />
| |
| **[[1y50]], [[1y51]] - GsHPr (mutant) <br />
| |
| **[[3ihs]] – HPr – ''Bacillus anthracis'' <br />
| |
|
| |
| *Phosphocarrier protein HPr complex
| |
|
| |
| **[[2jel]] - EcHPr + antibody <br />
| |
| **[[3eze]], [[3ezb]], [[3eza]] - EcHPr + EI N terminal + PO3 – NMR <br />
| |
| **[[2xdf]] - EcHPr + EI N terminal – NMR <br />
| |
| **[[1ggr]], [[1j6t]], [[1vrc]] - EcHPr + EII N terminal + PO3 – NMR <br />
| |
| **[[2lrk]], [[2lrl]] - EcHPr + EII N terminal – NMR <br />
| |
| **[[4xwj]] - EcHPr + antisigma factor RSD <br />
| |
| **[[5ya0]] - EcHPr + autoinducer-2 kinase <br />
| |
| **[[5ya1]] - EcHPr + autoinducer-2 kinase + ATP<br />
| |
| **[[5ya2]] - EcHPr + autoinducer-2 kinase + ADP<br />
| |
| **[[6kcr]] - EcHPr + mannitol operon repressor<br />
| |
| **[[1kkl]] - BsHPr (mutant) + HPrK <br />
| |
| **[[1kkm]] - BsHPr (mutant) with phosphoserine + HPrK/P <br />
| |
| **[[2fep]] - BsHPr with phosphoserine + BsCcpA <br />
| |
| **[[1rzr]] – BmHPr with phosphoserine + BmCcpA + DNA - ''Bacillus megaterium''<br />
| |
| **[[2oen]] - BmHPr with phosphoserine + BmCcpA<br />
| |
| **[[2nzu]] - BmHPr with phosphoserine + BmCcpA + glucose-6-phosphate <br />
| |
| **[[2nzv]] - BmHPr with phosphoserine + BmCcpA + fructose-1,6-diphosphate <br />
| |
| **[[3oqm]], [[3oqn]], [[3oqo]] - BsHPr with phosphoserine + BsCcpA + DNA<br />
| |
|
| |
| *Phosphocarrier protein NPr
| |
|
| |
| **[[5t17]], [[5t1n]] - EcNPr – NMR <br />
| |
| **[[5t1o]] - EcNPr + EIN-NTR – NMR <br />
| |
|
| |
| *Phosphocarrier protein III Glc
| |
|
| |
| **[[1f3g]] - EcPrcpIII <br />
| |
|
| |
| }}
| |
| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |