4pdc: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D== | ==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D== | ||
<StructureSection load='4pdc' size='340' side='right' caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='4pdc' size='340' side='right'caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cowpx Cowpx] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br> | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cowpx Cowpx] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br> | ||
| Line 10: | Line 10: | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | [[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
==See Also== | |||
*[[NK cell receptor|NK cell receptor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cowpx]] | [[Category: Cowpx]] | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Fremont, D H]] | [[Category: Fremont, D H]] | ||