6pvu: Difference between revisions

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'''Unreleased structure'''


The entry 6pvu is ON HOLD until Paper Publication
==RNase A in complex with hexametaphosphate==
 
<StructureSection load='6pvu' size='340' side='right'caption='[[6pvu]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6pvu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PVU FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P0S:2,4,6,8,10,12-hexahydroxy-2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~,10lambda~5~,12lambda~5~-cyclohexaphosphoxane-2,4,6,8,10,12-hexone'>P0S</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.18 4.6.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pvu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pvu OCA], [http://pdbe.org/6pvu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pvu RCSB], [http://www.ebi.ac.uk/pdbsum/6pvu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pvu ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pancreatic ribonuclease]]
[[Category: Cummins, C C]]
[[Category: Raines, R T]]
[[Category: Sheppard, S M]]
[[Category: Windsor, I W]]
[[Category: Lyase]]
[[Category: Nucleotide]]
[[Category: Poly-phosphate]]
[[Category: Rnase some]]

Revision as of 09:46, 6 November 2019

RNase A in complex with hexametaphosphateRNase A in complex with hexametaphosphate

Structural highlights

6pvu is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Pancreatic ribonuclease, with EC number 4.6.1.18
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

References

  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

6pvu, resolution 1.49Å

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