Synaptotagmin: Difference between revisions

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== Structural highlights ==
== Structural highlights ==


SYT-2 structure contains the SMP (synaptotagmin-like-mitochondrial-lipid binding) domain, followed by the <scene name='80/802718/Cv/2'>C2A Ca+2-binding, C2B</scene>, spacer and C2C domains. At the cup-shaped cavity at the of SYT C2A domain there are three tightly clustered Ca+2 binding sites formed by canonical 5 aspartates<ref>PMID:24373768</ref>.
SYT-2 structure contains the SMP (synaptotagmin-like-mitochondrial-lipid binding) domain, followed by the <scene name='80/802718/Cv/7'>C2A Ca+2-binding, C2B</scene>, spacer and C2C domains. At the cup-shaped cavity at the of SYT C2A domain there are three tightly clustered Ca+2 binding sites formed by canonical 5 aspartates<ref>PMID:24373768</ref>.
*<scene name='80/802718/Cv/3'>1st Ca+2 binding site</scene>. Water molecules shown as red spheres.
*<scene name='80/802718/Cv/8'>1st Ca+2 binding site</scene>. Water molecules are shown as red spheres.
*<scene name='80/802718/Cv/4'>2nd Ca+2 binding site</scene>.
*<scene name='80/802718/Cv/9'>2nd Ca+2 binding site</scene>.
*<scene name='80/802718/Cv/5'>3th Ca+2 binding site</scene>.
*<scene name='80/802718/Cv/10'>3th Ca+2 binding site</scene>.
*<scene name='80/802718/Cv/6'>All Ca+2 binding sites</scene>.
*<scene name='80/802718/Cv/11'>All Ca+2 binding sites</scene>.


</StructureSection>
</StructureSection>

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