6que: Difference between revisions

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'''Unreleased structure'''


The entry 6que is ON HOLD  until Paper Publication
==Structure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformation==
 
<StructureSection load='6que' size='340' side='right'caption='[[6que]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6que]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QUE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QUE FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qti|6qti]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6que FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6que OCA], [http://pdbe.org/6que PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6que RCSB], [http://www.ebi.ac.uk/pdbsum/6que PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6que ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NNTM_SHEEP NNTM_SHEEP]] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (By similarity).[UniProtKB:P07001][UniProtKB:Q13423]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Ovis aries]]
[[Category: Kampjut, D]]
[[Category: Sazanov, L A]]
[[Category: Membrane protein]]
[[Category: Mitochondrial]]
[[Category: Nicotinamide nucleotide transhydrogenase]]
[[Category: Proton-translocating]]

Revision as of 18:35, 28 August 2019

Structure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformationStructure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformation

Structural highlights

6que is a 2 chain structure with sequence from Ovis aries. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NNTM_SHEEP] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland (By similarity).[UniProtKB:P07001][UniProtKB:Q13423]

6que, resolution 3.70Å

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OCA
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