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==Crystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolution== | |||
<StructureSection load='6ac8' size='340' side='right'caption='[[6ac8]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ac8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AC8 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ac6|6ac6]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ac8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ac8 OCA], [http://pdbe.org/6ac8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ac8 RCSB], [http://www.ebi.ac.uk/pdbsum/6ac8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ac8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/I7G7M2_MYCS2 I7G7M2_MYCS2]] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Fox, G C]] | |||
[[Category: Nagaraja, V]] | |||
[[Category: Natesh, R]] | |||
[[Category: Putta, S]] | |||
[[Category: Rao, D N]] | |||
[[Category: Walsh, M A]] | |||
[[Category: Hydrolase]] | |||
[[Category: Mfd]] | |||
[[Category: Transcription coupled nucleotide excision repair]] | |||
[[Category: Transcription regulation]] | |||
[[Category: Transcription repair coupling factor]] | |||
Revision as of 18:17, 28 August 2019
Crystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolutionCrystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolution
Structural highlights
Function[I7G7M2_MYCS2] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969] |
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