6afk: Difference between revisions

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'''Unreleased structure'''


The entry 6afk is ON HOLD  until Paper Publication
==Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor==
 
<StructureSection load='6afk' size='340' side='right'caption='[[6afk]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
Authors: Zhong, W., Koay, A., Wong, Y.W., Sahili, A.E., Nah, Q., Kang, C., Poulsen, A., Chionh, Y.K., McBee, M., Matter, A., Hill, J., Lescar, J., Dedon, P.C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6afk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AFK FirstGlance]. <br>
Description: Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9WO:N-{(3S)-1-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperidin-3-yl}-1H-indole-2-carboxamide'>9WO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6afk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6afk OCA], [http://pdbe.org/6afk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6afk RCSB], [http://www.ebi.ac.uk/pdbsum/6afk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6afk ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_PSEAB TRMD_PSEAB]] Specifically methylates guanosine-37 in various tRNAs.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Chionh, Y K]]
[[Category: Dedon, P C]]
[[Category: Hill, J]]
[[Category: Hill, J]]
[[Category: Kang, C]]
[[Category: Koay, A]]
[[Category: Lescar, J]]
[[Category: Lescar, J]]
[[Category: Matter, A]]
[[Category: Matter, A]]
[[Category: McBee, M]]
[[Category: Nah, Q]]
[[Category: Poulsen, A]]
[[Category: Poulsen, A]]
[[Category: Mcbee, M]]
[[Category: Sahili, A E]]
[[Category: Wong, Y.W]]
[[Category: Wong, Y W]]
[[Category: Koay, A]]
[[Category: Kang, C]]
[[Category: Sahili, A.E]]
[[Category: Nah, Q]]
[[Category: Dedon, P.C]]
[[Category: Zhong, W]]
[[Category: Zhong, W]]
[[Category: Chionh, Y.K]]
[[Category: Transferase]]
[[Category: Trna methyltransferase]]

Revision as of 19:24, 14 August 2019

Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitorCrystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor

Structural highlights

6afk is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:tRNA (guanine(37)-N(1))-methyltransferase, with EC number 2.1.1.228
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TRMD_PSEAB] Specifically methylates guanosine-37 in various tRNAs.

6afk, resolution 2.75Å

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OCA