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==Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor== | |||
<StructureSection load='6afk' size='340' side='right'caption='[[6afk]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6afk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AFK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9WO:N-{(3S)-1-[3-(pyridin-4-yl)-1H-pyrazol-5-yl]piperidin-3-yl}-1H-indole-2-carboxamide'>9WO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6afk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6afk OCA], [http://pdbe.org/6afk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6afk RCSB], [http://www.ebi.ac.uk/pdbsum/6afk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6afk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRMD_PSEAB TRMD_PSEAB]] Specifically methylates guanosine-37 in various tRNAs. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Chionh, Y K]] | |||
[[Category: Dedon, P C]] | |||
[[Category: Hill, J]] | [[Category: Hill, J]] | ||
[[Category: Kang, C]] | |||
[[Category: Koay, A]] | |||
[[Category: Lescar, J]] | [[Category: Lescar, J]] | ||
[[Category: Matter, A]] | [[Category: Matter, A]] | ||
[[Category: McBee, M]] | |||
[[Category: Nah, Q]] | |||
[[Category: Poulsen, A]] | [[Category: Poulsen, A]] | ||
[[Category: | [[Category: Sahili, A E]] | ||
[[Category: Wong, Y | [[Category: Wong, Y W]] | ||
[[Category: Zhong, W]] | [[Category: Zhong, W]] | ||
[[Category: | [[Category: Transferase]] | ||
[[Category: Trna methyltransferase]] |
Revision as of 19:24, 14 August 2019
Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitorCrystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor
Structural highlights
Function[TRMD_PSEAB] Specifically methylates guanosine-37 in various tRNAs. |
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