GTPase KRas: Difference between revisions
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*<scene name='78/781207/Cv/8'>Mg coordination site</scene>. | *<scene name='78/781207/Cv/8'>Mg coordination site</scene>. | ||
*<scene name='78/781207/Cv/10'>GDP/Mg binding cleft</scene>. | *<scene name='78/781207/Cv/10'>GDP/Mg binding cleft</scene>. | ||
== 3D Structures of GTPase KRas == | |||
[[GTPase KRas 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of GTPase KRas == | == 3D Structures of GTPase KRas == | ||
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**[[5uk9]] – hKRas + GCP + GDP – human <br /> | **[[5uk9]] – hKRas + GCP + GDP – human <br /> | ||
**[[5vq2]] – hKRas + GTP <br /> | **[[5vq2]] – hKRas + GTP <br /> | ||
**[[6god]] – hKRas + GPPNP <br /> | |||
**[[6goe]], [[6gof]], [[6gog]], [[6gom]] – hKRas (mutant) + GPPNP <br /> | |||
**[[5w22]], [[4obe]], [[4lpk]], [[5vq8]] – hKRas + GDP <br /> | **[[5w22]], [[4obe]], [[4lpk]], [[5vq8]] – hKRas + GDP <br /> | ||
**[[3gft]] – hKRas (mutant) + GTP analog <br /> | **[[3gft]] – hKRas (mutant) + GTP analog <br /> | ||
**[[4l8g]], [[4ldj]], [[4ql3]], [[4tq9]], [[4tqa]], [[6asa]], [[6ase]], [[5whd]], [[5uqw]], [[5us4]], [[5vp7]], [[5vq0]], [[5vq1]], [[4wa7]], [[4lrw]] – hKRas (mutant) + GDP <br /> | **[[4l8g]], [[4ldj]], [[4ql3]], [[4tq9]], [[4tqa]], [[6asa]], [[6ase]], [[5whd]], [[5uqw]], [[5us4]], [[5vp7]], [[5vq0]], [[5vq1]], [[4wa7]], [[4lrw]], [[6bof]] – hKRas (mutant) + GDP <br /> | ||
**[[5vpi]], [[5vpz]], [[5vq6]] – hKRas (mutant) + GTP <br /> | **[[5vpi]], [[5vpz]], [[5vq6]] – hKRas (mutant) + GTP <br /> | ||
**[[5usj]], [[5vpy]] – hKRas (mutant) + GNP <br /> | **[[5usj]], [[5vpy]] – hKRas (mutant) + GNP <br /> | ||
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**[[5kyk]] – hKRas + inhibitor <br /> | **[[5kyk]] – hKRas + inhibitor <br /> | ||
**[[4nmm]] – hKRas (mutant) + inhibitor <br /> | **[[4nmm]] – hKRas (mutant) + inhibitor <br /> | ||
**[[5v9o]], [[5f2e]], [[5v9u]], [[4dsu]], [[4luc]], [[4lv6]], [[4lyf]], [[4lyh]], [[4lyj]], [[4m1o]], [[4m1s]], [[4m1t]], [[4m1w]], [[4m1y]], [[4m21]], [[4m22]], [[4epr]], [[4ept]], [[4epv]], [[4epw]], [[4epx]], [[4epy]], [[4q01]], [[4q02]], [[4q03]], [[5vbm]], [[5v6s]], [[5v6v]], [[6ark]], [[5xco]], [[6b0v]], [[6b0y]], [[5yxz]], [[5yy1]], [[4pzy]], [[4pzz]] – hKRas (mutant) + GDP + inhibitor <br /> | **[[5v9o]], [[5f2e]], [[5v9u]], [[4dsu]], [[4luc]], [[4lv6]], [[4lyf]], [[4lyh]], [[4lyj]], [[4m1o]], [[4m1s]], [[4m1t]], [[4m1w]], [[4m1y]], [[4m21]], [[4m22]], [[4epr]], [[4ept]], [[4epv]], [[4epw]], [[4epx]], [[4epy]], [[4q01]], [[4q02]], [[4q03]], [[5vbm]], [[5v6s]], [[5v6v]], [[6ark]], [[5xco]], [[6b0v]], [[6b0y]], [[5yxz]], [[5yy1]], [[4pzy]], [[4pzz]], [[6n2j]], [[6n2k]] – hKRas (mutant) + GDP + inhibitor <br /> | ||
**[[5vbz]] – hKRas (mutant) + GNP + inhibitor <br /> | **[[5vbz]], [[6gqy]], [[6gqw]], [[6gqx]], [[6gqt]] – hKRas (mutant) + GNP + inhibitor <br /> | ||
**[[6fa1]], [[6fa2]], [[6fa3]], [[6fa4]], [[5oct]], [[5oco]], [[5ocg]] – hKRas (mutant) + GNP + inhibitor<br /> | |||
**[[6f76]] – hKRas (mutant) + GPPNP + inhibitor<br /> | |||
**[[5v71]], [[5v9l]] – hKRas (mutant) + GDP + quinazoline inhibitor <br /> | **[[5v71]], [[5v9l]] – hKRas (mutant) + GDP + quinazoline inhibitor <br /> | ||
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**[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br /> | **[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br /> | ||
**[[5wpl]], [[5whe]], [[5wpm]], [[5wlb]] – hKRas (mutant) + miniprotein + GNP <br /> | **[[5wpl]], [[5whe]], [[5wpm]], [[5wlb]] – hKRas (mutant) + miniprotein + GNP <br /> | ||
**[[6h46]] – hKRas + darpin K13 + GDP <br /> | |||
**[[6h47]] – hKRas + darpin K19 <br /> | |||
**[[5o2s]], [[5mlb]] – hKRas + darpin K27 + GDP <br /> | **[[5o2s]], [[5mlb]] – hKRas + darpin K27 + GDP <br /> | ||
**[[5tb5]], [[5tar]] – hKRas + GMP-PDE d + farnesyl + GDP <br /> | **[[5tb5]], [[5tar]] – hKRas + GMP-PDE d + farnesyl + GDP <br /> | ||
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**[[2msc]], [[2msd]] – hKRas + apolipoprotein + GDP - NMR<br /> | **[[2msc]], [[2msd]] – hKRas + apolipoprotein + GDP - NMR<br /> | ||
**[[2mse]] – hKRas + apolipoprotein + A-Raf + GDP - NMR<br /> | **[[2mse]] – hKRas + apolipoprotein + A-Raf + GDP - NMR<br /> | ||
**[[6ccx]], [[6cch]], [[6cc9]] – hKRas (mutant) + apolipoprotein + inhibitor + GPPNP - NMR<br /> | |||
**[[6epl]] – hKRas (mutant) + son of sevenless homolog 1<br /> | |||
**[[6epm]], [[6epn]], [[6epo]], [[6epp]] – hKRas (mutant) + son of sevenless homolog 1 + inhibitor<br /> | |||
}} | }} | ||