1vol: Difference between revisions

Revision as of 09:40, 24 April 2008

TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX

OverviewOverview

The crystal structure of the transcription factor IIB (TFIIB)/TATA box-binding protein (TBP)/TATA-element ternary complex is described at 2.7 A resolution. Core TFIIB resembles cyclin A, and recognizes the preformed TBP-DNA complex through protein-protein and protein-DNA interactions. The amino-terminal domain of core TFIIB forms the downstream surface of the ternary complex, where it could fix the transcription start site. The remaining surfaces of TBP and the TFIIB can interact with TBP-associated factors, other class II initiation factors, and transcriptional activators and coactivators.

About this StructureAbout this Structure

1VOL is a Protein complex structure of sequences from Arabidopsis thaliana and Homo sapiens. The following page contains interesting information on the relation of 1VOL with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of a TFIIB-TBP-TATA-element ternary complex., Nikolov DB, Chen H, Halay ED, Usheva AA, Hisatake K, Lee DK, Roeder RG, Burley SK, Nature. 1995 Sep 14;377(6545):119-28. PMID:7675079 Page seeded by OCA on Thu Apr 24 09:40:21 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1vol.jpg|left|200px]]
- {{Structure
+<!--
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+The line below this paragraph, containing "STRUCTURE_1vol", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY=
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1vol|  PDB=1vol  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vol OCA], [http://www.ebi.ac.uk/pdbsum/1vol PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vol RCSB]</span>
-}}
 '''TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX'''
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 [[Category: Roeder, R G.]]
 [[Category: Usheva, A U.]]
-[[Category: complex]]
+[[Category: Complex]]
-[[Category: dna]]
+[[Category: Dna]]
-[[Category: molecular recognition]]
+[[Category: Molecular recognition]]
-[[Category: transcription factor]]
+[[Category: Transcription factor]]
-[[Category: transcription initiation]]
+[[Category: Transcription initiation]]
-[[Category: transcription regulation]]
+[[Category: Transcription regulation]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:40:21 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:26:40 2008''