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==Co-Crystal structure of P. aeruginosa LpxC-50228 complex== | |||
<StructureSection load='6mo5' size='340' side='right'caption='[[6mo5]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6mo5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MO5 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JWP:N-[(2S)-1-(hydroxyamino)-3-methyl-3-{[(oxetan-3-yl)methyl]sulfonyl}-1-oxobutan-2-yl]-4-(6-hydroxyhexa-1,3-diyn-1-yl)benzamide'>JWP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-3-O-acyl-N-acetylglucosamine_deacetylase UDP-3-O-acyl-N-acetylglucosamine deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.108 3.5.1.108] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mo5 OCA], [http://pdbe.org/6mo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mo5 RCSB], [http://www.ebi.ac.uk/pdbsum/6mo5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mo5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | |||
[[Category: Andrews, L]] | |||
[[Category: Assar, Z]] | |||
[[Category: Cirz, R]] | [[Category: Cirz, R]] | ||
[[Category: Cohen, F]] | [[Category: Cohen, F]] | ||
[[Category: | [[Category: Holt, M C]] | ||
[[Category: | [[Category: Stein, A J]] | ||
[[Category: Hydrolase]] | |||
[[Category: Hydrolase lpxc pseudomonas aeruginosa]] | |||
[[Category: Hydrolase-inhibitor complex]] |
Revision as of 13:44, 17 July 2019
Co-Crystal structure of P. aeruginosa LpxC-50228 complexCo-Crystal structure of P. aeruginosa LpxC-50228 complex
Structural highlights
Function[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. |
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