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Glyceraldehyde-3-Phosphate Dehydrogenase: Difference between revisions

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For additional information, see: [[Carbohydrate Metabolism]]
For additional information, see: [[Carbohydrate Metabolism]]
<br />
<br />
==3D structures of glyceraldehyde-3-phosphate dehydrogenase==
[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
</StructureSection>
</StructureSection>


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*Apo GAPDH
*Apo GAPDH


**[[5c7l]] - hGAPDH – human<br />
**[[5c7i]] - mGAPDH – mouse<br />
**[[4gpd]], [[1crw]] – AlGAPDH – American lobster<br />
**[[2hki]] – sGAPDH – spinach<br />
**[[3e6a]] – RiGAPDH ligand binding domain – rice<br />
**[[4iq8]] - GAPDH – yeast<br />
**[[1vsu]] – CpGAPDH – ''Cryptosporidium parvum''<br />
**[[1vsu]] – CpGAPDH – ''Cryptosporidium parvum''<br />
**[[1dc5]], [[1s7c]], [[5o0v]] - EcGAPDH – ''Escherichia coli''<br />
**[[1dc5]], [[1s7c]], [[5o0v]], [[6io4]] - EcGAPDH – ''Escherichia coli''<br />
**[[6io4]], [[6io6]], [[6ioj]] - EcGAPDH (mutant) <br />
**[[1euh]], [[1qi6]] - SmGAPDH – ''Streptococcus mutans''<br />
**[[1euh]], [[1qi6]] - SmGAPDH – ''Streptococcus mutans''<br />
**[[5m6d]] - GAPDH – ''Streptococcus pneumoniae''<br />
**[[5m6d]] - GAPDH – ''Streptococcus pneumoniae''<br />
**[[2hki]] – sGAPDH – spinach<br />
**[[3e6a]] – RiGAPDH ligand binding domain – rice<br />
**[[3lc7]], [[5t73]] - SaGAPDH – ''Staphylococcus aureus''<br />
**[[3lc7]], [[5t73]] - SaGAPDH – ''Staphylococcus aureus''<br />
**[[3pqa]] – MjGAPDH – ''Methanocaldococcus jannaschii''<br />
**[[3pqa]] – MjGAPDH – ''Methanocaldococcus jannaschii''<br />
**[[3prl]] – BhGAPDH – ''Bacillus halodurans''<br />
**[[3prl]] – BhGAPDH – ''Bacillus halodurans''<br />
**[[5c7i]] - mGAPDH – mouse<br />
**[[5c7l]] - hGAPDH – human<br />
**[[4iq8]] - GAPDH – yeast<br />
**[[4gpd]], [[1crw]] – AlGAPDH – American lobster<br />
**[[4dib]] – GAPDH – ''Bacillus anthracis''<br />
**[[4dib]] – GAPDH – ''Bacillus anthracis''<br />
**[[2gd1]] – GsGAPDH – ''Geobacillus stearothermophilus''<br />
**[[2gd1]] – GsGAPDH – ''Geobacillus stearothermophilus''<br />
**[[1obf]] – GAPDH – ''Achromobacter xylosoxidans''<br />
**[[1obf]] – GAPDH – ''Achromobacter xylosoxidans''<br />
**[[1b7g]] - GAPDH – ''Sulfolobus solfataricus''<br />
**[[1b7g]] - GAPDH – ''Sulfolobus solfataricus''<br />
**[[5v8y]], [[5v8x]] - SagGAPDH (mutant) – ''Streptococcus agalactiae''<br />
**[[6iep]] - SagGAPDH – ''Streptococcus agalactiae''<br />
**[[5v8y]], [[5v8x]] - SagGAPDH (mutant) <br />
**[[6iqv]] - LpGAPDH – ''Lactobacillus plantarum''<br />


*NAD-dependent GAPDH with cofactor NAD
*NAD-dependent GAPDH with cofactor NAD


**[[3gpd]], [[1znq]], [[1u8f]], [[5c7o]], [[4wnc]], [[3pfw]] - hGAPDH + NAD <br />
**[[4wni]], [[6ade]] - hGAPDH (mutant) + NAD<br />
**[[5ddi]] - pGAPDH + NAD – pig<br />
**[[4o63]], [[4o59]] - bGAPDH + NAD – bovine<br />
**[[1j0x]] - GAPDH + NAD – rabbit<br />
**[[2vyn]], [[2vyv]] - GAPDH + NAD - rat<br />
**[[1ihx]] – scsGAPDH + NAD derivative – South China Sea lobster<br />
**[[1gpd]], [[1szj]], [[1dss]]  – AlGAPDH + NAD <br />
**[[1nbo]] - sGAPDH + NAD<br />
**[[3pym]] - yGAPDH + NAD <br />
**[[1vsv]], [[3cps]] – CpGAPDH + NAD<br />
**[[1vsv]], [[3cps]] – CpGAPDH + NAD<br />
**[[1gpd]], [[1szj]], [[1dss]]  – AlGAPDH + NAD – American lobster<br />
**[[3gpd]], [[1znq]], [[1u8f]], [[5c7o]], [[4wnc]], [[3pfw]] - GAPDH + NAD <br />
**[[4wni]] - hGAPDH (mutant) + NAD<br />
**[[2vyn]], [[2vyv]] - GAPDH + NAD - rat<br />
**[[1gd1]], [[3cmc]] – GsGAPDH + NAD – ''Geobacillus stearothermophilus''<br />
**[[1gd1]], [[3cmc]] – GsGAPDH + NAD – ''Geobacillus stearothermophilus''<br />
**[[1dbv]], [[3dbv]], [[1nq5]], [[1npt]] - GsGAPDH (mutant) + NAD<br />
**[[1dbv]], [[3dbv]], [[1nq5]], [[1npt]] - GsGAPDH (mutant) + NAD<br />
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**[[1gae]] - EcGAPDH (mutant) + NAD<br />
**[[1gae]] - EcGAPDH (mutant) + NAD<br />
**[[2ep7]] – GAPDH + NAD – ''Aquifex aeolicus''<br />
**[[2ep7]] – GAPDH + NAD – ''Aquifex aeolicus''<br />
**[[1nbo]] - sGAPDH + NAD<br />
**[[1j0x]] - GAPDH + NAD – rabbit<br />
**[[2b4r]], [[1ywg]] - PfGAPDH + NAD – ''Plasmodium falciparum''<br />
**[[2b4r]], [[1ywg]] - PfGAPDH + NAD – ''Plasmodium falciparum''<br />
**[[2b4t]] - PfGAPDH (mutant) + NAD<br />
**[[2b4t]] - PfGAPDH (mutant) + NAD<br />
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**[[3hq4]], [[3k9q]], [[3ksd]], [[3lc1]], [[3kv3]] - SaGAPDH (mutant) + NAD<br />
**[[3hq4]], [[3k9q]], [[3ksd]], [[3lc1]], [[3kv3]] - SaGAPDH (mutant) + NAD<br />
**[[3lvf]], [[3vaz]] - SaGAPDH + NAD<br />
**[[3lvf]], [[3vaz]] - SaGAPDH + NAD<br />
**[[3pfw]] - hGAPDH + NAD – human<br />
**[[3sth]] - GAPDH + NAD – ''Toxoplasma gondii''<br />
**[[3sth]] - GAPDH + NAD – ''Toxoplasma gondii''<br />
**[[3pym]] - yGAPDH + NAD – yeast<br />
**[[5vmt]] - GAPDH + NAD – ''Neisseria gonorrhoeae''<br />
**[[5vmt]] - GAPDH + NAD – ''Neisseria gonorrhoeae''<br />
**[[5jy6]], [[5jye]], [[5jyf]], [[4qx6]], [[5y37]] - SagGAPDH + NAD – ''Streptococcus agalactiae''<br />
**[[5jy6]], [[5jye]], [[5jyf]], [[4qx6]], [[5y37]] - SagGAPDH + NAD – ''Streptococcus agalactiae''<br />
**[[5jya]], [[5utm]], [[5utl]] - SagGAPDH (mutant) + NAD<br />
**[[5jya]], [[5utm]], [[5utl]] - SagGAPDH (mutant) + NAD<br />
**[[5ddi]] - pGAPDH + NAD – pig<br />
**[[4o63]], [[4o59]] - bGAPDH + NAD – bovine<br />
**[[4k9d]] - GAPDH + NAD – ''Brugia malayi''<br />
**[[4k9d]] - GAPDH + NAD – ''Brugia malayi''<br />
**[[4boy]], [[3zcx]], [[3b20]] - SeGAPDH + NAD – ''Synechococcus elongatus''<br />
**[[4boy]], [[3zcx]], [[3b20]], [[6gfr]] - SeGAPDH + NAD – ''Synechococcus elongatus''<br />
**[[3l0d]] - GAPDH + NAD – ''Bartonella henselae''<br />
**[[3l0d]] - GAPDH + NAD – ''Bartonella henselae''<br />
**[[3doc]] - GAPDH + NAD – ''Brucella melitensis''<br />
**[[3doc]] - GAPDH + NAD – ''Brucella melitensis''<br />
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**[[5ld5]] - GAPDH + NAD – ''Atopobium vaginae''<br />
**[[5ld5]] - GAPDH + NAD – ''Atopobium vaginae''<br />
**[[4lsm]] - TcGAPDH  + NAD – ''Trypanosoma cruzi''<br />
**[[4lsm]] - TcGAPDH  + NAD – ''Trypanosoma cruzi''<br />
**[[1ihx]] – scsGAPDH + NAD derivative – South China Sea lobster<br />
**[[6ok4]] - GAPDH + NAD – ''Chlamydia trachomatis''<br />
**[[6nlx]] - GAPDH + NAD – ''Naegleria fowleri''<br />
**[[6iqm]] - LpGAPDH + NAD<br />
**[[6fzi]] - GAPDH + NAD – ''Clostridium perfringens''<br />
**[[6fzh]] - GAPDH + NAD – ''Streptococcus pyogenes''<br />
**[[6dfz]] - GAPDH + NAD – ''Acropora millepora''<br />


*NAD-dependent GAPDH ternary complexes containing glyceraldehyde-3-phosphate (G3P)
*NAD-dependent GAPDH ternary complexes containing glyceraldehyde-3-phosphate (G3P)
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*Other NAD-dependent GAPDH ternary complexes
*Other NAD-dependent GAPDH ternary complexes


**[[3h9e]] - hGAPDH + NAD + phosphate<br />
**[[5tso]] - pGAPDH + NAD + phenanthroline <br />
**[[1ihy]] – scsGAPDH + ADP-ribose <br />
**[[3dmt]], [[3ids]] - TcGAPDH  + NAD + inhibitor<br />
**[[3dmt]], [[3ids]] - TcGAPDH  + NAD + inhibitor<br />
**[[3h9e]] - hGAPDH + NAD + phosphate<br />
**[[3k73]], [[3l6o]] - SaGAPDH + NAD + phosphate<br />
**[[3k73]], [[3l6o]] - SaGAPDH + NAD + phosphate<br />
**[[1uxt]] - TtGAPDH (mutant) + NAD + G1P<br />
**[[1uxt]] - TtGAPDH (mutant) + NAD + G1P<br />
**[[3b1j]], [[3b1k]], [[3zdf]] - SeGAPDH + NAD + CP12 <br />
**[[3b1j]], [[3b1k]], [[3zdf]], [[6ghr]], [[6ghl]], [[6gg7]], [[6gfq]], [[6gfo]] - SeGAPDH + NAD + CP12 <br />
**[[6gfp]] - SeGAPDH + NAD + NADP <br />
**[[6gve]] - SeGAPDH + NAD + CP12 + phosphoribulokinase<br />
**[[3qv1]] - AtGAPDH + NAD + CP12 <br />
**[[3qv1]] - AtGAPDH + NAD + CP12 <br />
**[[5tso]] - pGAPDH + NAD + phenanthroline <br />
**[[1i33]], [[1i32]] - LmGAPDH  + inhibitor<br />
**[[1i33]], [[1i32]] - LmGAPDH  + inhibitor<br />
**[[1ihy]] – scsGAPDH + ADP-ribose <br />
**[[5za0]] – EcGAPDH-A + trehalose<br />
**[[5za0]] – EcGAPDH-A + trehalose<br />


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*NADP-dependent GAPDH with cofactor NADP
*NADP-dependent GAPDH with cofactor NADP


**[[1jn0]], [[1rm4]], [[2pkq]], [[2pkr]] - sGAPDH  + NADP<br />
**[[1rm3]], [[1rm5]] - sGAPDH (mutant) + NADP<br />
**[[2dbv]], [[4dbv]] - GsGAPDH (mutant) + NADP<br />
**[[2dbv]], [[4dbv]] - GsGAPDH (mutant) + NADP<br />
**[[2yyy]] - MjGAPDH + NADP<br />
**[[2yyy]] - MjGAPDH + NADP<br />
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**[[2id2]] - SmGAPDH (mutant) + NADP<br />
**[[2id2]] - SmGAPDH (mutant) + NADP<br />
**[[1cf2]] - GAPDH + NADP – ''Methanothermus fervidus''<br />
**[[1cf2]] - GAPDH + NADP – ''Methanothermus fervidus''<br />
**[[1jn0]], [[1rm4]], [[2pkq]], [[2pkr]] - sGAPDH  + NADP<br />
**[[1ky8]], [[1uxn]] - TtGAPDH + NADP – ''Thermoproteus tenax''<br />
**[[1rm3]], [[1rm5]] - sGAPDH (mutant) + NADP<br />
**[[1ky8]] - TtGAPDH + NADP – ''Thermoproteus tenax''<br />
**[[3rhh]] - BhGAPDH + NADP<br />
**[[3rhh]] - BhGAPDH + NADP<br />


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Nathan Line, David Canner, Andrew Swart, Alice Harmon, Michal Harel, Alexander Berchansky
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