Macrophage inhibitory factor: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
MIF contains two different catalytic sites. A phenylpyruvate tautomerase site is located in the N terminal. A <scene name='55/551208/Cv/ | MIF contains two different catalytic sites. A phenylpyruvate tautomerase site is located in the N terminal. A <scene name='55/551208/Cv/5'>disulfide reductase site is located in the tetrapeptide Cys-Ala-Leu-Cys in position 57-60</scene>. The <scene name='55/551208/Cv/6'>inhibitor binds to the pro-inflammatory tautomerase site</scene><ref>PMID:17526494</ref>. Water molecules shown as red spheres. | ||
</StructureSection> | </StructureSection> | ||