1ih4: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Multi-Conformation Crystal Structure of GGm5CGCC== | ==Multi-Conformation Crystal Structure of GGm5CGCC== | ||
<StructureSection load='1ih4' size='340' side='right' caption='[[1ih4]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='1ih4' size='340' side='right'caption='[[1ih4]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ih4]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IH4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ih4]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IH4 FirstGlance]. <br> | ||
| Line 21: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Henderson, K]] | [[Category: Henderson, K]] | ||
[[Category: Ho, P S]] | [[Category: Ho, P S]] | ||
Revision as of 10:17, 3 July 2019
Multi-Conformation Crystal Structure of GGm5CGCCMulti-Conformation Crystal Structure of GGm5CGCC
Structural highlights
Publication Abstract from PubMedThe transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway. A crystallographic map of the transition from B-DNA to A-DNA.,Vargason JM, Henderson K, Ho PS Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:11390969[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
|
| ||||||||||||||||||