Fibroblast growth factor receptor: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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<scene name='54/544712/Cv/2'>Human fibroblast growth factor receptor 1 ligand-binding domain modules D2 and D3 with 2 molecules of fibroblast growth factor 1</scene> (PDB code [[1evt]]). | <scene name='54/544712/Cv/2'>Human fibroblast growth factor receptor 1 ligand-binding domain modules D2 and D3 with 2 molecules of fibroblast growth factor 1</scene> (PDB code [[1evt]]). | ||
==3D structures of fibroblast growth factor receptor== | |||
[[Fibroblast growth factor receptor 3D receptor]] | |||
</StructureSection> | </StructureSection> | ||
==3D structures of fibroblast growth factor receptor== | ==3D structures of fibroblast growth factor receptor== | ||
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*''FGFR1 tyrosine kinase domain residues 458-765'' | *''FGFR1 tyrosine kinase domain residues 458-765'' | ||
**[[4uwy]], [[6mzq]] – hFGFR1 TKD - human<br /> | |||
**[[1fgk]], [[3kxx]], [[3ky2]], [[4rwi]], [[5flf]] – hFGFR1 TKD (mutant) - human <br /> | **[[1fgk]], [[3kxx]], [[3ky2]], [[4rwi]], [[5flf]] – hFGFR1 TKD (mutant) - human <br /> | ||
**[[ | **[[4wun]], [[5am6]], [[5ew8]], [[5o49]], [[5o4a], [[6mzw]], [[6c1o]] – hFGFR1 TKD + inhibitor <br /> | ||
**[[1agw]], [[1fgi]], [[2fgi]], [[3c4f]], [[3js2]], [[3rhx]], [[4f63]], [[4f64]], [[4f65]], [[3tt0]], [[4nk9]], [[4nka]], [[4nks]], [[5b7v]], [[5am7]], [[4rwj]], [[4rwk]], [[4rwl]], [[4uwb]], [[4uwc]], [[4zsa]], [[5uq0]], [[5vnd]], [[5ur1]], [[6p68]], [[6p69]], [[6c18]], [[6c19]], [[6c1b]], [[6c1c]], [[5z0s]] – hFGFR1 TKD (mutant) + inhibitor <br /> | |||
**[[1agw]], [[1fgi]], [[2fgi]], [[3c4f]], [[3js2]], [[3rhx]], [[4f63]], [[4f64]], [[4f65]], [[3tt0]], [[4nk9]], [[4nka]], [[4nks]], [[5b7v]], [[5am7]], [[4rwj]], [[4rwk]], [[4rwl]], [[4uwb]], [[4uwc]], [[4zsa]], [[5uq0]], [[5vnd]], [[5ur1]] | **[[5zv2]] – hFGFR1 TKD (mutant) + anti-cancer drug<br /> | ||
**[[3krj]] – hFGFR1 TKD residues 538-678, 753-922 (mutant) + inhibitor <br /> | **[[3krj]] – hFGFR1 TKD residues 538-678, 753-922 (mutant) + inhibitor <br /> | ||
**[[1xr0]] – hFGFR1 residues 409-430 + FGFR signaling adaptor N terminal - NMR<br /> | **[[1xr0]] – hFGFR1 residues 409-430 + FGFR signaling adaptor N terminal - NMR<br /> | ||
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**[[4qqj]], [[4qqt]] – hFGFR4 TKD (mutant) <br /> | **[[4qqj]], [[4qqt]] – hFGFR4 TKD (mutant) <br /> | ||
**[[5jkg]], [[5nwz]], [[5nud]] – hFGFR4 TKD + inhibitor<br /> | **[[5jkg]], [[5nwz]], [[5nud]] – hFGFR4 TKD + inhibitor<br /> | ||
**[[6jpj]], [[5xff]], [[5xfj]] – hFGFR4 TKD (mutant) + inhibitor<br /> | |||
**[[4qrc]], [[4r6v]], [[4qqc]], [[4qq5]], [[4uxq]], [[4xcu]] – hFGFR4 TKD (mutant) + irreversible inhibitor<br /> | **[[4qrc]], [[4r6v]], [[4qqc]], [[4qq5]], [[4uxq]], [[4xcu]] – hFGFR4 TKD (mutant) + irreversible inhibitor<br /> | ||