5a2g: Difference between revisions
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==An esterase from anaerobic Clostridium hathewayi can hydrolyze aliphatic aromatic polyesters== | ==An esterase from anaerobic Clostridium hathewayi can hydrolyze aliphatic aromatic polyesters== | ||
<StructureSection load='5a2g' size='340' side='right' caption='[[5a2g]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5a2g' size='340' side='right'caption='[[5a2g]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5a2g]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A2G FirstGlance]. <br> | <table><tr><td colspan='2'>[[5a2g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_hathewayi_dsm_13479 Clostridium hathewayi dsm 13479]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A2G FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a2g OCA], [http://pdbe.org/5a2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a2g RCSB], [http://www.ebi.ac.uk/pdbsum/5a2g PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a2g OCA], [http://pdbe.org/5a2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a2g RCSB], [http://www.ebi.ac.uk/pdbsum/5a2g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a2g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5a2g" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5a2g" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Clostridium hathewayi dsm 13479]] | |||
[[Category: Large Structures]] | |||
[[Category: Baumschlager, A]] | [[Category: Baumschlager, A]] | ||
[[Category: Bleymaier, K]] | [[Category: Bleymaier, K]] | ||
Revision as of 11:09, 26 June 2019
An esterase from anaerobic Clostridium hathewayi can hydrolyze aliphatic aromatic polyestersAn esterase from anaerobic Clostridium hathewayi can hydrolyze aliphatic aromatic polyesters
Structural highlights
Publication Abstract from PubMedRecently, a variety of biodegradable polymers have been developed as alternatives to recalcitrant materials. Although many studies on polyester biodegradability have focused on aerobic environments, there is much less known on biodegradation of polyesters in natural and artificial anaerobic habitats. Consequently, the potential of anaerobic biogas sludge to hydrolyze the synthetic compostable polyester PBAT (poly(butylene adipate-co-butylene terephthalate) was evaluated in this study. On the basis of reverse-phase high-performance liquid chromatography (RP-HPLC) analysis, accumulation of terephthalic acid (Ta) was observed in all anaerobic batches within the first 14 days. Thereafter, a decline of Ta was observed, which occurred presumably due to consumption by the microbial population. The esterase Chath_Est1 from the anaerobic risk 1 strain Clostridium hathewayi DSM-13479 was found to hydrolyze PBAT. Detailed characterization of this esterase including elucidation of the crystal structure was performed. The crystal structure indicates that Chath_Est1 belongs to the alpha/beta-hydrolases family. This study gives a clear hint that also micro-organisms in anaerobic habitats can degrade manmade PBAT. An Esterase from Anaerobic Clostridium hathewayi Can Hydrolyze Aliphatic-Aromatic Polyesters.,Perz V, Hromic A, Baumschlager A, Steinkellner G, Pavkov-Keller T, Gruber K, Bleymaier K, Zitzenbacher S, Zankel A, Mayrhofer C, Sinkel C, Kueper U, Schlegel K, Ribitsch D, Guebitz GM Environ Sci Technol. 2016 Feb 29. PMID:26878094[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Clostridium hathewayi dsm 13479
- Large Structures
- Baumschlager, A
- Bleymaier, K
- Gruber, K
- Guebitz, G M
- Hromic, A
- Keller, T Pavkov
- Kueper, U
- Mayrhofer, C
- Perz, V
- Ribitsch, D
- Schlegel, K A
- Sinkel, C
- Steinkellner, G
- Zankel, A
- Zitzenbacher, S
- Anaerobic biodegradation
- Anaerobic esterase
- Biogas batch
- Clostridium hathewayi
- Hydrolase
- Microbial polyesterase
- Polyester biodegradation