6o11: Difference between revisions

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-'''Unreleased structure'''
-The entry 6o11 is ON HOLD  until Paper Publication
+==E. coli cysteine desulfurase SufS C364A with a Cys-aldimine intermediate==
+<StructureSection load='6o11' size='340' side='right'caption='[[6o11]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6o11]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O11 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O11 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C6P:N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE'>C6P</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o11 OCA], [http://pdbe.org/6o11 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o11 RCSB], [http://www.ebi.ac.uk/pdbsum/6o11 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o11 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SUFS_ECOLI SUFS_ECOLI]] Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.<ref>PMID:10829016</ref> <ref>PMID:12089140</ref> <ref>PMID:11997471</ref> <ref>PMID:12876288</ref> <ref>PMID:12941942</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Dunkle, J A]]
+[[Category: Frantom, P A]]
+[[Category: Cysteine desulfurase]]
+[[Category: Lyase]]
+[[Category: Persulfide]]
+[[Category: Plp]]
+[[Category: Suf]]
+[[Category: Transferase]]