6f8j: Difference between revisions

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-'''Unreleased structure'''
-The entry 6f8j is ON HOLD  until Paper Publication
+==Crystal Structure of E. coli GyraseB 24kDa in complex with 6-[(ethylcarbamoyl)amino]-4-(1H-pyrazol-1-yl)-N-(pyridin-3-yl)pyridine-3-carboxamide==
+<StructureSection load='6f8j' size='340' side='right'caption='[[6f8j]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6f8j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F8J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F8J FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CZ5:6-(ethylcarbamoylamino)-4-pyrazol-1-yl-~{N}-pyridin-3-yl-pyridine-3-carboxamide'>CZ5</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f8j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f8j OCA], [http://pdbe.org/6f8j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f8j RCSB], [http://www.ebi.ac.uk/pdbsum/6f8j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f8j ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GYRB_ECO57 GYRB_ECO57]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.[HAMAP-Rule:MF_01898]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Fishwick, C W.G]]
+[[Category: Lawson, D M]]
+[[Category: Maxwell, A]]
+[[Category: Narramore, S K]]
+[[Category: Stevenson, C E.M]]
+[[Category: Binding site]]
+[[Category: Dna gyrase]]
+[[Category: Inhibitor]]
+[[Category: Isomerase]]
+[[Category: Pyridine-3-carboxamide]]
+[[Category: Topoisomerase iv]]