6go5: Difference between revisions
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==TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate== | |||
<StructureSection load='6go5' size='340' side='right'caption='[[6go5]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6go5]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GO5 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XC5:2-DEOXY-5-O-[(S)-HYDROXY{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]METHYL}PHOSPHORYL]CYTIDINE'>XC5</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6go5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6go5 OCA], [http://pdbe.org/6go5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6go5 RCSB], [http://www.ebi.ac.uk/pdbsum/6go5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6go5 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Delarue, M]] | |||
[[Category: Gerodimos, C A]] | |||
[[Category: Lieber, M R]] | |||
[[Category: Rosario, S]] | [[Category: Rosario, S]] | ||
[[Category: | [[Category: H, J Loc]] | ||
[[Category: | [[Category: Dna binding protein]] | ||
[[Category: | [[Category: Dna bridging]] | ||
[[Category: | [[Category: Dna polymerase polx]] | ||
[[Category: Nhej pathway]] |