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==Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin== | ==Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin== | ||
<StructureSection load='4xe9' size='340' side='right' caption='[[4xe9]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='4xe9' size='340' side='right'caption='[[4xe9]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4xe9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4xe9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE9 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanB, SP_1687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe9 OCA], [http://pdbe.org/4xe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe9 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe9 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe9 OCA], [http://pdbe.org/4xe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe9 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xe9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
==See Also== | |||
*[[Sialidase|Sialidase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
[[Category: Large Structures]] | |||
[[Category: Strpn]] | |||
[[Category: Brear, P]] | [[Category: Brear, P]] | ||
[[Category: Allosteric inhibitor]] | [[Category: Allosteric inhibitor]] | ||
Revision as of 10:09, 29 May 2019
Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with OptactinCrystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin
Structural highlights
See Also |
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