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==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolate== | ==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolate== | ||
<StructureSection load='4tt8' size='340' side='right' caption='[[4tt8]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4tt8' size='340' side='right'caption='[[4tt8]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4tt8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TT8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4tt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TT8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6DD:N-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)METHYL](FORMYL)AMINO}BENZOYL)-L-GLUTAMIC+ACID'>6DD</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6DD:N-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)METHYL](FORMYL)AMINO}BENZOYL)-L-GLUTAMIC+ACID'>6DD</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ts4|4ts4]], [[4tts|4tts]], [[4qpd|4qpd]], [[4qpc|4qpc]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ts4|4ts4]], [[4tts|4tts]], [[4qpd|4qpd]], [[4qpc|4qpc]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aldh1l1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tt8 OCA], [http://pdbe.org/4tt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tt8 RCSB], [http://www.ebi.ac.uk/pdbsum/4tt8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tt8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tt8 OCA], [http://pdbe.org/4tt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tt8 RCSB], [http://www.ebi.ac.uk/pdbsum/4tt8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tt8 ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Brachidanio rerio]] | |||
[[Category: Formyltetrahydrofolate dehydrogenase]] | [[Category: Formyltetrahydrofolate dehydrogenase]] | ||
[[Category: Large Structures]] | |||
[[Category: Chang, W N]] | [[Category: Chang, W N]] | ||
[[Category: Chen, C J]] | [[Category: Chen, C J]] | ||
Revision as of 17:57, 10 May 2019
Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolateCrystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolate
Structural highlights
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