190d: Difference between revisions
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==Crystal structure of a four-stranded intercalated DNA: d(C4)== | ==Crystal structure of a four-stranded intercalated DNA: d(C4)== | ||
<StructureSection load='190d' size='340' side='right' caption='[[190d]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='190d' size='340' side='right'caption='[[190d]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[190d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=190D FirstGlance]. <br> | <table><tr><td colspan='2'>[[190d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=190D FirstGlance]. <br> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Cai, L]] | [[Category: Cai, L]] | ||
[[Category: Chen, L]] | [[Category: Chen, L]] | ||
Revision as of 17:24, 10 May 2019
Crystal structure of a four-stranded intercalated DNA: d(C4)Crystal structure of a four-stranded intercalated DNA: d(C4)
Structural highlights
Publication Abstract from PubMedThe crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested. Crystal structure of a four-stranded intercalated DNA: d(C4).,Chen L, Cai L, Zhang X, Rich A Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References |
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