5izb: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Murin CXCL13 solution structure featuring a folded N-terminal domain== | ==Murin CXCL13 solution structure featuring a folded N-terminal domain== | ||
<StructureSection load='5izb' size='340' side='right' caption='[[5izb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='5izb' size='340' side='right'caption='[[5izb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5izb]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IZB FirstGlance]. <br> | <table><tr><td colspan='2'>[[5izb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IZB FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [http://pdbe.org/5izb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [http://www.ebi.ac.uk/pdbsum/5izb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cxcl13, Blc, Scyb13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [http://pdbe.org/5izb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [http://www.ebi.ac.uk/pdbsum/5izb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE]] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs. | [[http://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE]] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs. | ||
==See Also== | |||
*[[C-X-C motif chemokine|C-X-C motif chemokine]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lk3 transgenic mice]] | |||
[[Category: Lortat-Jacob, H]] | [[Category: Lortat-Jacob, H]] | ||
[[Category: Monneau, Y R]] | [[Category: Monneau, Y R]] | ||
[[Category: Chemokine structure n-terminal domain conformational exchange]] | [[Category: Chemokine structure n-terminal domain conformational exchange]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 16:03, 10 May 2019
Murin CXCL13 solution structure featuring a folded N-terminal domainMurin CXCL13 solution structure featuring a folded N-terminal domain
Structural highlights
Function[CXL13_MOUSE] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs. See Also |
| ||||||||||||||||