Chitinase: Difference between revisions
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== Function == | == Function == | ||
[[Chitinase]]s cleave the beta-1-4-glycosidic bond between the N-acetyl-D-glucosamine units of which chitin is comprised. Chitinases are present in plants, bacteria and fungi. The first chitinase structures were solved in 1994, from a bacterium ([[1ctn]]) and a plant ([[2hvm]]). A mechanism for chitin cleavage was proposed based on several structures and was later confirmed. <ref>PMID:21054166</ref> | [[Chitinase]]s (Chi) cleave the beta-1-4-glycosidic bond between the N-acetyl-D-glucosamine units of which chitin is comprised. Chitinases are present in plants, bacteria and fungi. The first chitinase structures were solved in 1994, from a bacterium ([[1ctn]]) and a plant ([[2hvm]]). A mechanism for chitin cleavage was proposed based on several structures and was later confirmed. <ref>PMID:21054166</ref>. <br /> | ||
* '''Chitinase I''' is found in plants.<br /> | |||
* '''Chitinase II''' is found in plants, fungi and bacteria.<br /> | |||
* '''Chitinase III''' has no sequence similarity to class I or II.<br /> | |||
* '''Chitinase IV''' has similar characteristics to class I but are smaller than it.<br /> | |||
==Disease == | ==Disease == | ||
Chi is related to allergies and asthma. | Chi is related to allergies and asthma<ref>PMID:19295241</ref>. | ||
== Structural highlights == | == Structural highlights == | ||