6r7z: Difference between revisions

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-'''Unreleased structure'''
-The entry 6r7z is ON HOLD
+==CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)==
+<StructureSection load='6r7z' size='340' side='right'caption='[[6r7z]], [[Resolution|resolution]] 5.14&Aring;' scene=''>
-Authors: Pike, A.C.W., Bushell, S.R., Shintre, C.A., Tessitore, A., Chu, A., Mukhopadhyay, S., Shrestha, L., Chalk, R., Burgess-Brown, N.A., Love, J., Huiskonen, J.T., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6r7z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R7Z FirstGlance]. <br>
-Description: CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r7z OCA], [http://pdbe.org/6r7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r7z RCSB], [http://www.ebi.ac.uk/pdbsum/6r7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r7z ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Shintre, C.A]]
+== Disease ==
-[[Category: Pike, A.C.W]]
+[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Adult-onset autosomal recessive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry.
-[[Category: Arrowsmith, C.H]]
+== Function ==
+[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.<ref>PMID:20056604</ref> <ref>PMID:22946059</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
+[[Category: Burgess-Brown, N A]]
+[[Category: Bushell, S R]]
+[[Category: Carpenter, E P]]
 [[Category: Chalk, R]]
+[[Category: Chu, A]]
+[[Category: Edwards, A M]]
+[[Category: Huiskonen, J T]]
+[[Category: Love, J]]
+[[Category: Mukhopadhyay, S]]
+[[Category: Pike, A C.W]]
+[[Category: Structural genomic]]
+[[Category: Shintre, C A]]
 [[Category: Shrestha, L]]
-[[Category: Love, J]]
-[[Category: Burgess-Brown, N.A]]
-[[Category: Huiskonen, J.T]]
-[[Category: Chu, A]]
 [[Category: Tessitore, A]]
-[[Category: Edwards, A.M]]
+[[Category: Calcium activation]]
-[[Category: Mukhopadhyay, S]]
+[[Category: Lipid transport]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: Membrane protein]]
-[[Category: Carpenter, E.P]]
+[[Category: Sgc]]
-[[Category: Bountra, C]]
+[[Category: Transport protein]]
-[[Category: Bushell, S.R]]