Hsp70: Difference between revisions

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Parkinson’s Disease is characterized by continuing loss of dopaminergic neurons in the substantia nigra pars compacta, with subsequent dopamine decline in the nigrostriatal pathway, and by intracytoplasmic fibrillar α-Syn protein aggregates (Lewy Bodies, LB) in the remaining nigral neurons.  Hsp70 overexpression demonstrated reduced α-Syn accumulation and toxicity in both mouse and Drosophila Parkinson’s Disease Models <ref>Turturici, G., Sconzo, G., & Geraci, F. (2011). Hsp70 and Its Molecular Role in Nervous System Diseases. Biochemistry Research International, 2011, 1-18. doi:10.1155/2011/618127</ref>.
Parkinson’s Disease is characterized by continuing loss of dopaminergic neurons in the substantia nigra pars compacta, with subsequent dopamine decline in the nigrostriatal pathway, and by intracytoplasmic fibrillar α-Syn protein aggregates (Lewy Bodies, LB) in the remaining nigral neurons.  Hsp70 overexpression demonstrated reduced α-Syn accumulation and toxicity in both mouse and Drosophila Parkinson’s Disease Models <ref>Turturici, G., Sconzo, G., & Geraci, F. (2011). Hsp70 and Its Molecular Role in Nervous System Diseases. Biochemistry Research International, 2011, 1-18. doi:10.1155/2011/618127</ref>.
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


== References ==
== References ==
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