6me4: Difference between revisions

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-'''Unreleased structure'''
-The entry 6me4 is ON HOLD  until Paper Publication
+==XFEL crystal structure of human melatonin receptor MT1 in complex with 2-iodomelatonin==
+<StructureSection load='6me4' size='340' side='right'caption='[[6me4]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6me4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ME4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ME4 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ML2:N-[2-(2-IODO-5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML2</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6me4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6me4 OCA], [http://pdbe.org/6me4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6me4 RCSB], [http://www.ebi.ac.uk/pdbsum/6me4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6me4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/MTR1A_HUMAN MTR1A_HUMAN]] High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Batyuk, A]]
+[[Category: Brehm, W]]
+[[Category: Cherezov, V]]
+[[Category: Gati, C]]
+[[Category: Grandner, J M]]
+[[Category: Grant, T D]]
+[[Category: Han, G W]]
+[[Category: Ishchenko, A]]
+[[Category: Johansson, L C]]
+[[Category: Katritch, V]]
+[[Category: Liu, W]]
+[[Category: Madsen, C]]
+[[Category: McCorvy, J D]]
+[[Category: Michaelian, N]]
+[[Category: Olsen, R H.J]]
+[[Category: Patel, N]]
+[[Category: Roth, B L]]
+[[Category: Stauch, B]]
+[[Category: Tribo, A R]]
+[[Category: Weierstall, U]]
+[[Category: White, T A]]
+[[Category: Zhu, L]]
+[[Category: 2-iodomelatonin]]
+[[Category: Circadian rhythm]]
+[[Category: Gpcr]]
+[[Category: Jetlag]]
+[[Category: Lcp]]
+[[Category: Membrane protein]]
+[[Category: Pg]]
+[[Category: Xfel]]