|
|
| Line 23: |
Line 23: |
| </StructureSection> | | </StructureSection> |
|
| |
|
| ==3D structures of BChE==
| |
|
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| * hBChE - Apo human
| |
|
| |
| **[[2pm8]], [[1p0i]] - hBChE - human <br />
| |
| **[[2xmb]] – hBChE (mutant)+SO4<br />
| |
| **[[2xmc]] - hBChE (mutant)+F <br />
| |
| **[[4aqd]] - hBChE (fully glycosylated)
| |
|
| |
| * BChE+OP irreversible inhibitors, including nerve agents and insecticides
| |
|
| |
| **[[3djy]], [[3dkk]] - hBChE+tabun <br />
| |
| **[[2wid]], [[2wif]] - hBChE+Tabun analogue TA1 <br />
| |
| **[[2wsl]], [[2wig]] – hBChE+Tabun analogue TA4 <br />
| |
| **[[2wil]], [[2wij]] - hBChE+Tabun analogue TA5 <br />
| |
| **[[2wik]] - hBChE+Tabun analogue TA6 <br />
| |
| **[[1xlw]] - hBChE+echothiophate <br />
| |
| **[[1xmd]], [[2xmd]] – hBChE (mutant)+echothiophate<br />
| |
| **[[1p0q]] - hBChE+soman <br />
| |
| **[[1xlu]] - hBChE+Di-Isopropyl-Phosphoro-Fluoridate (DFP)<br />
| |
| **[[2xmg]] - hBChE (mutant)+VX<br />
| |
| **[[1xlv]] – hBChE+ethyl dihydrogen phosphate<br />
| |
| **[[2y1k]], [[4bbz]] - hBChE (mutant) + CBDP <br />
| |
| **[[4b0p]], [[4b0o]] - hBChE (Aged) + pyridinium derivative<br />
| |
| **[[4axb]] – hBChE (aged) + 2-PAM
| |
|
| |
| * BChE+inhibitor binding at surface of the protein (far from the active site)
| |
|
| |
| **[[2j4c]] – hBChE+ HgCl2 <br />
| |
|
| |
| * BChE + substrate analogues mimicking the binding of the substrate butyrylcholine
| |
|
| |
| **[[1p0m]] - hBChE+choline <br />
| |
| **[[1p0p]] - hBChE+butyrylthiocholine<br />
| |
| **[[3o9m]] - hBChE + benzoic acid<br />
| |
| **[[1eho]], [[1ehq]], [[1kcj]] – hBChE + cocaine - model<br />
| |
| **[[4bds]], [[6i0b]] – hBChE + tacrine derivative<br />
| |
| }}
| |
| ==Additional Resources== | | ==Additional Resources== |
| For additional information, see: [[Alzheimer's Disease]] | | For additional information, see: [[Alzheimer's Disease]] |