4pt6: Difference between revisions
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==The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities== | ==The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities== | ||
<StructureSection load='4pt6' size='340' side='right' caption='[[4pt6]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4pt6' size='340' side='right'caption='[[4pt6]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4pt6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PT6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4pt6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PT6 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pt6 OCA], [http://pdbe.org/4pt6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pt6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pt6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pt6 ProSAT]</span></td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F8, F8C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pt6 OCA], [http://pdbe.org/4pt6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pt6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pt6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pt6 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/FA8_HUMAN FA8_HUMAN]] Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. | [[http://www.uniprot.org/uniprot/FA8_HUMAN FA8_HUMAN]] Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. | ||
==See Also== | |||
*[[Factor VIII|Factor VIII]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Hamdouche, S]] | [[Category: Hamdouche, S]] | ||
[[Category: Kamajaya, A]] | [[Category: Kamajaya, A]] | ||