Bone morphogenetic protein: Difference between revisions
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BMP-7 is involved in chronic kidney disease<ref>PMID:18508541</ref>. | BMP-7 is involved in chronic kidney disease<ref>PMID:18508541</ref>. | ||
==3D structures of bone morphogenetic protein== | |||
[[Bone morphogenetic protein 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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**[[3edg]], [[3edh]] – hBMP protease domain – human<br /> | **[[3edg]], [[3edh]] – hBMP protease domain – human<br /> | ||
**[[6bsl]], [[6bsm]][, [[6btn]], [[6bto]], [[6btp]], [[6btq]] – hBMP protease domain + inhibitor<br /> | |||
*Bone morphogenetic protein 2 | *Bone morphogenetic protein 2 | ||
Revision as of 10:50, 16 April 2019
FunctionBone morphogenetic protein (BMP) are growth factors which can induce formation of bone and cartllage'[1]. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-2 see Student Projects for UMass Chemistry 423 Spring 2012-4. RelevanceRecombinant BMP is used in oral surgery and spinal fusion. DiseaseBMP-7 is involved in chronic kidney disease[2]. 3D structures of bone morphogenetic proteinBone morphogenetic protein 3D structures
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3D structures of bone morphogenetic protein3D structures of bone morphogenetic protein
Updated on 16-April-2019
ReferencesReferences
- ↑ Reddi AH, Reddi A. Bone morphogenetic proteins (BMPs): from morphogens to metabologens. Cytokine Growth Factor Rev. 2009 Oct-Dec;20(5-6):341-2. doi:, 10.1016/j.cytogfr.2009.10.015. Epub 2009 Nov 8. PMID:19900831 doi:http://dx.doi.org/10.1016/j.cytogfr.2009.10.015
- ↑ Mitu G, Hirschberg R. Bone morphogenetic protein-7 (BMP7) in chronic kidney disease. Front Biosci. 2008 May 1;13:4726-39. PMID:18508541