Formate dehydrogenase: Difference between revisions
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'''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>. | '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>. | ||
*<scene name='49/491980/Cv/ | *<scene name='49/491980/Cv/8'>NAD binding site</scene> in NAD-dependent formate dehydrogenase ([[2nad]]). Water molecules shown as red spheres. | ||
*<scene name='49/491980/Cv/ | *<scene name='49/491980/Cv/9'>Azide ion binding site</scene>. | ||
</StructureSection> | </StructureSection> | ||
==3D structure of formate dehydrogenase== | ==3D structure of formate dehydrogenase== | ||