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==Human caspase-6 E35K== | |||
<StructureSection load='6dev' size='340' side='right'caption='[[6dev]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dev]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DEV FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-6 Caspase-6], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.59 3.4.22.59] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dev OCA], [http://pdbe.org/6dev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dev RCSB], [http://www.ebi.ac.uk/pdbsum/6dev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dev ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caspase-6]] | |||
[[Category: Large Structures]] | |||
[[Category: Beautrait, A]] | |||
[[Category: Deny, L J]] | |||
[[Category: Gorelik, A]] | |||
[[Category: LeBlanc, A C]] | |||
[[Category: Lukacs, G L]] | |||
[[Category: Lynham, J]] | |||
[[Category: Marinier, A]] | |||
[[Category: Nagar, B]] | |||
[[Category: Sharma, G]] | |||
[[Category: Soya, N]] | |||
[[Category: Tubeleviciute-Aydin, A]] | |||
[[Category: Hydrolase]] | |||
Revision as of 09:33, 27 March 2019
Human caspase-6 E35KHuman caspase-6 E35K
Structural highlights
Function[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. |
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