5qhg: Difference between revisions

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-'''Unreleased structure'''
-The entry 5qhg is ON HOLD
+==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NU000442a==
+<StructureSection load='5qhg' size='340' side='right'caption='[[5qhg]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
-Authors: Krojer, T., Talon, R., Fairhead, M., Diaz Saez, L., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Ruda, G.F., Szommer, T., Srikannathasan, V., Elkins, J., Spencer, J., London, N., Nelson, A., Brennan, P.E., Huber, K., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5qhg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHG FirstGlance]. <br>
-Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of NUDT7 in complex with NU000442a
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H17:2-{3-[(2R)-1-acryloylpyrrolidin-2-yl]phenyl}-N-(3-chlorophenyl)acetamide'>H17</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
-[[Category: Spencer, J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhg OCA], [http://pdbe.org/5qhg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhg RCSB], [http://www.ebi.ac.uk/pdbsum/5qhg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN]] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Aimon, A]]
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
+[[Category: Bradley, A R]]
+[[Category: Brandao-Neto, J]]
+[[Category: Brennan, P E]]
+[[Category: Collins, P]]
+[[Category: Delft, F von]]
+[[Category: Douangamath, A]]
+[[Category: Edwards, A]]
 [[Category: Elkins, J]]
-[[Category: Collins, P]]
+[[Category: Fairhead, M]]
 [[Category: Huber, K]]
-[[Category: Ruda, G.F]]
-[[Category: Arrowsmith, C.H]]
-[[Category: Brandao-Neto, J]]
-[[Category: Diaz Saez, L]]
-[[Category: Fairhead, M]]
-[[Category: Von Delft, F]]
-[[Category: Bradley, A.R]]
-[[Category: Talon, R]]
-[[Category: Brennan, P.E]]
-[[Category: Edwards, A]]
-[[Category: Douangamath, A]]
-[[Category: Szommer, T]]
 [[Category: Krojer, T]]
+[[Category: London, N]]
+[[Category: Nelson, A]]
+[[Category: Ruda, G F]]
+[[Category: Saez, L Diaz]]
+[[Category: Spencer, J]]
 [[Category: Srikannathasan, V]]
-[[Category: Bountra, C]]
+[[Category: Szommer, T]]
-[[Category: Nelson, A]]
+[[Category: Talon, R]]
-[[Category: London, N]]
+[[Category: Hydrolase]]
+[[Category: Nudix domain]]
+[[Category: Pandda]]
+[[Category: Sgc - diamond i04-1 fragment screening]]
+[[Category: Xchemexplorer]]