6q5f: Difference between revisions

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-'''Unreleased structure'''
-The entry 6q5f is ON HOLD  until Paper Publication
+==OXA-48_P68A-CAZ. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance==
+<StructureSection load='6q5f' size='340' side='right'caption='[[6q5f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Frohlich, C., Sorum, V., Thomassen, A.M., Johnsen, P.J., Leiros, H.-K.S., Samuelsen, O.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6q5f]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q5F FirstGlance]. <br>
-Description: OXA-48_P68A-CAZ. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CTJ:1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-{[(2-CARBOXYPROPAN-2-YL)OXY]IMINO}ACETYL]AMINO}-2-OXOETHYL]-4-CARBOXY-3,6-DIHYDRO-2H-1,3-THIAZIN-5-YL}METHYL)PYRIDINIUM'>CTJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q5f OCA], [http://pdbe.org/6q5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q5f RCSB], [http://www.ebi.ac.uk/pdbsum/6q5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q5f ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Beta-lactamase]]
+[[Category: Large Structures]]
+[[Category: Frohlich, C]]
+[[Category: Johnsen, P J]]
+[[Category: Leiros, H K.S]]
 [[Category: Samuelsen, O]]
-[[Category: Leiros, H.-K.S]]
-[[Category: Frohlich, C]]
 [[Category: Sorum, V]]
-[[Category: Johnsen, P.J]]
+[[Category: Thomassen, A M]]
-[[Category: Thomassen, A.M]]
+[[Category: Antibiotic]]
+[[Category: Avibactam]]
+[[Category: Carbapenem]]
+[[Category: Carbapenemase]]
+[[Category: Ceftazidime]]
+[[Category: Escherichia coli]]
+[[Category: Evolution]]
+[[Category: Klebsiella pneumoniae]]
+[[Category: Oxa-48]]
+[[Category: Resistance development]]