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Aminoacyl tRNA Synthetase: Difference between revisions

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</StructureSection>
</StructureSection>
== 3D Structures of Aminoacyl tRNA synthetase ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*'''Class I aaRS'''
*'''Arg-RS'''
**[[1bs2]] – yArgRS<br />
**[[3gdz]] – ArgRS  residues 1-106 – ''Klebsiella pneumoniae''<br />
**[[1iq0]] – TtArgRS  - ''Thermus thermophilus''
*''Arg-RS + tRNA''
**[[2zuf]] - PhArgRS  + Arg-tRNA - ''Pyrococcus horikoshii''<br />
**[[1f7v]] - yArgRS  + Arg-tRNA
*''Arg-RS ternary complex''
**[[1f7u]] – yArgRS  + Arg-tRNA + Arg<br />
**[[2zue]] – PhArgRS  + Arg-tRNA + ATP analog
*'''Cys-RS'''
**[[1li5]] - EcCysRS - ''Escherichia coli''<br />
**[[1li7]] - EcCysRS + Cys<br />
**[[1u0b]] – EcCysRS + Cys-tRNA
*'''Gln-RS'''
**[[1nyl]]– EcGlnRS<br />
**[[2gls]], [[1lgr]] – StGlnRS – ''Salmonella typhimurium''<br />
**[[4p2b]] – GlnRS catalytic domain – ''Toxoplasma gondii''<br /`>
**[[2lgs]] – StGlnRS + Glu<br />
**[[1qrt]], [[1qru]], [[1qrs]] - EcGlnRS (mutant) + Gln-tRNA<br />
**[[1gtr]], [[1gts]], [[1gsg]] - EcGlnRS + Gln-tRNA<br />
**[[1qtq]] - EcGlnRS + Gln-tRNA + Gln analog
*''Gln-RS ternary complex''
**[[1euq]], [[ 1euy]] – EcGlnRS + Gln-tRNA + Gln-SA<br />
**[[1exd]] - EcGlnRS + Gln-tRNA (mutant) + AMP
*'''Glu-RS'''
**[[1gln]] – TtGluRS<br />
**[[2o5r]] - TmGluRS<br />
**[[3aii]] – GluRS – ''Methanothermobacter thermautotrophicus''<br />
**[[2ja2]] – MtGluRS – ''Mycobacterium tuberculosis''<br />
**[[4a91]] – EcGluRS<br />
**[[2hz7]] – DrGluRS – ''Deinococcus radiodurans''<br />
**[[2hra]] – yGluRS N-terminal
*''Glu-RS + small substrates or analogs''
**[[3afh]] - TmGluRS + Glu-AMP analog<br />
**[[2rd2]], [[ 2re8]] – EcGluRS (mutant) + Glu-SA<br />
**[[2cuz]] – TtGluRS + Glu<br />
**[[1j09]] - TtGluRS + Glu + ATP<br />
**[[1n75]] - TtGluRS + ATP<br />
**[[2fco]] - GluRS residues 2-485 + Glu – ''Synechococcus elongatus''
*''Glu-RS + tRNA''
**[[1zjw]] – EcGluRS + Glu-tRNA
*''Glu-RS ternary complex''
**[[3akz]], [[ 3al0]] – TmGluRS + tRNA + Glu-AMP analog – ''Thermotoga maritima''<br />
**[[1o0b]], [[ 1o0c]] - EcGluRS + Glu-tRNA + Glu + AMP<br />[[2cv0]], [[ 1n77]] - TtGluRS + Glu + Glu-tRNA<br />
**[[1n78]] - TtGluRS + Glu-ol + Glu-tRNA<br />
**[[2cv1]] - TtGluRS + Glu-ol + ATP + Glu-tRNA<br />
**[[2cv2]] - TtGluRS + Glu-SA + Glu-tRNA<br />
**[[2hrk]], [[ 2hsm]] - yGluRS N-terminal + GU4 nucleic-binding protein 1<br />
**[[5bmu]] – hGluRS GST-like domain + EPRS-AIMP3<br />
*'''Ile-RS'''
**[[1ile]] - TtIleRS<br />
**[[1wny]], [[ 1udz]] – TtIleRS editing domain
*''Ile-RS + small substrates or analogs''<br />
**[[1ue0]] - TtIleRS editing domain + Val<br />
**[[1wnz]] - TtIleS editing domain + Val-adenylate<br />
**[[1wk8]] - TtIleRS editing domain + Val-SA<br />
**[[1jzq]] – TtIleS + Ile-adenylate analog<br />
**[[1jzs]] – TtIleS + antibiotic
*''Ile-RS ternary complex''<br />
**[[1ffy]], [[ 1qu2]], [[ 1qu3]] - SaIleRS + Ile-tRNA + antibiotic - ''Staphylococcus aureus''
*'''Leu-RS'''
**[[3o0a]] – AaLeuRS hydrolytic domain – ''Aquifex aeolicus''<br />[[2wfd]] – hLeuRS editing domain – human<br />
**[[2wfe]] - CaLeuRS editing domain – ''Candida albicans''<br />
**[[2ajg]] - EcLeuRS editing domain<br />
**[[1wkb]] – PhLeuRS residues 1-810
*''Leu-RS + small substrates or analogs''<br />
**[[2wfg]] - CaLeuRS editing domain + benzoxaborole-AMP<br />
**[[2v0c]] – TtLeuRS + Leu-SA + benzoxaborole-AMP<br />
**[[1h3n]] - TtLeuRS + Leu-SA<br />
**[[1obc]], [[1obh]] – TtLeuRS + substrate analog<br />
**[[2ajh]], [[2aji]] - EcLeuRS editing domain + aa
*''Leu-RS + tRNA''<br />
**[[1wz2]] – PhLeuRS Leu-tRNA
*''Leu-RS ternary complex''<br />
**[[2v0g]] - TtLeuRS + Leu-tRNA + benzoxaborole-AMP<br />
**[[2bte]], [[ 2byt]] - TtLeuRS + Leu-tRNA + Leu
*'''Lys-RS'''
**[[1irx]] – PhLysRS<br />
**[[1bbw]] – EcLysRS<br />
**[[1krs]], [[ 1krt]] – EcLysRS anticodon-binding domain – NMR<br />
**[[3dsq]] – DhLysRS – ''Desulfitobacterium hafniense''<br />
**[[3bju]] – hLysRS residues 70-579
*''Lys-RS + small substrates or analogs''<br />
**[[3a74]] – GsLysRS + diadenosine tetraphosphate – ''Geobacillus stearothermophilus''<br />
**[[3e9h]], [[3e9i]] – BsLysRS + Lys-SA - ''Bacillus stearothermophilus''<br />
**[[1bbu]], [[1e10]], [[1lyl]] – EcLysRS + Lys<br />
**[[1e1t]] - EcLysRS + Lys-adenylate<br />
**[[1e22]] - EcLysRS + Lys + AMPPCP<br />
**[[1e24]] - EcLysRS + Lys + ATP
*''Lys-RS + tRNA''<br />
**[[2zni]], [[2znj]] – DhLysRS + tRNA
*'''Met-RS'''
**[[1a8h]] – TtMetRS<br />
**[[1med]], [[1mea]] – EcMetRS Zinc-binding domain - NMR<br />
**[[1qqt]] - EcMetRS residues 2-552<br />
**[[2x1l]] - MsMetRS residues 2-515 – ''Mycobacterium smegmatis''<br />
**[[3h97]] – EcMetRS residues 2-548 (mutant) <br />
**[[3h9c]] - EcMetRS residues 2-548<br />
**[[2d54]], [[2d5b]] – TtMetRS (mutant) <br />
**[[1woy]] – TtMetRS residues 1-500 (mutant) <br />
**[[2djv]] – hMetRS WHEP-TRS domain – NMR<br />
**[[1pyb]] – AaMetRS β subunit<br />
**[[1rqg]] – PaMetRS – ''Pyrococcus abyssi''<br />
**[[1mkh]] – PaMetRS C-terminal
*''Met-RS + small substrates or analogs''<br />
**[[3kfl]] – LmMetRS residues 206-747+ Met-adenylate - ''Leishmania major''<br />
**[[2x1m]] - MsMetRS residues 2-515 + Met<br />
**[[1p7p]], [[1pfu]], [[1pfv]], [[1pfw]] - EcMetRS residues 2-548 + Met<br />
**[[1pfy]] - EcMetRS residues 1-551 + Met-SA<br />
**[[1f4l]] - EcMetRS residues 1-551 + Met<br />
**[[1pg0]] - EcMetRS residues 1-551 + Met-adenylate<br />
**[[1pg2]] - EcMetRS residues 1-551 + Met + adenine<br />
**[[3h99]] - EcMetRS residues 2-548 (mutant) + Met<br />
**[[3h9b]] - EcMetRS residues 2-548 (mutant) + azidonorleucine<br />
**[[4dlp]] - BmMetRS + SMet – ''Brucella melitensis''<br />
**[[4py2]] – BmMetRS + inhibitor<br />
*''Met-RS + tRNA''<br />
**[[2csx]] – AaMetRS + Met-tRNA
*''Met-RS + tRNA''<br />
**[[2ct8]] - AaMetRS + Met-tRNA + Met-SA<br />
**[[2dxi]] – TtMetRS + tRNA + ATP + Glu-ol
*''Met-RS coplex''<br />
**[[4bl7]], [[4bvx]], [[4bvy]] - hMetRS N-terminal + elongation factor P18<br />
**[[2hsn]] - yMetRS N-terminal + GU4 nucleic-binding protein 1 N-terminal
*'''Trp-RS'''
**[[1d2r]] - GsTrpRS<br />
**[[3prh]] – TrpRS (mutant) – ''Bacillus subtilis''<br />
**[[3n9i]] – TrpRS – ''Yarsinia pestis''<br />
**[[3m5w]] – CjTrpRS – ''Campylobacter jejuni''<br />
**[[3a04]] – ApTrpRS – ''Aeropyrum pernix''<br />
**[[3hzr]] – EhTrpRS – ''Entamoeba histolytica'' <br />
**[[3i05]] – TbTrpRS residues 3-389 – ''Trypanosoma brucei''<br />
**[[3hv0]] – CpTrpRS residues 206-593 – ''Cryptosporidium parvum''<br />
**[[3foc]] – GlTrpRS – ''Giardia lamblia''<br />
**[[1o5t]] – hTrpRS catalytic fragment<br />
**[[1ulh]] – hTrpRS residues 35-424<br />
**[[2el7]] – TtTrpRS<br />
**[[2ip1]], [[3kt0]] – yTrpRS – yeast<br />
**[[2yy5]] – TrpRS – ''Mycoplasma pneumoniae''<br />
**[[2g36]] – TmTrpRS<br />
**[[1bks]] – StTrpRS + pyridoxal phosphate
*''Trp-RS + small substrates or analogs''<br />
**[[3a05]] – ApTrpRS + Trp<br />
**[[3kt3]] – yTrpRS + Trp-adenylate<br />
**[[3kt6]], [[3kt8]] – yTrpRS + Trp<br />
**[[3jxe]] – PhTrpRS + Trp-adenylate<br />
**[[3fhj]], [[3ghd]] – BsTrpRS + Trp + AMP + Pi<br />
**[[2quh]] – hTrpRS + Trp<br />
**[[2qui]] - hTrpRS + Trp-amide + ATP<br />
**[[2quj]] - hTrpRS + Trp-adenylate<br />
**[[2quk]] – hTrpRS + ATP<br />
**[[2ov4]] – GsTrpRS + adenosine tetraphosphate<br />
**[[1i6k]], [[1i6l]], [[1i6m]] – GsTrpRS + Trp-adenylate<br />
**[[1yid]], [[2a4m]] – DrTrpRS + ATP<br />
**[[1yi8]], [[1yia]] – DrTrpRS + Trp<br />
**[[1mau]] – GsTrpRS + Trp + ATP<br />
**[[1maw]], [[ 1m83]] - GsTrpRS + ATP<br />
**[[1mb2]] - GsTrpRS + Trp <br />
**[[3tze]] - TrpRS + Trp - ''Encephalitozoon cuniculi''<br />
**[[3tzl]] - CjTrpRS + Trp + ADP<br />
**[[3sz3]] - TrpRS + Trp - ''Vibrio cholerae''<br />
**[[6dfu]] - TrpRS + Trp - ''Haemophillus influenzae''<br />
*''Trp-RS + tRNA''<br />
**[[2ake]], [[2dr2]] - hTrpRS + Trp-tRNA
*'''Tyr-RS'''
**[[1tya]], [[ 1tyb]], [[ 1tyc]], [[ 1tyd]], [[ 2ts1]] – GsTyrRS<br />
**[[3qe4]], [[3d6u]], [[3d6v]], [[2pxh]], [[2hgz]], [[1u7d]] – MjTyrRS – ''Methanocaldococcus jannaschii''<br />
**[[1u7x]], [[4hjr]], [[4hk4]]- MjTyrRS (mutant) <br />
**[[2jan]] – MtTyrRS<br />
**[[1y42]] - NcTyrRS  – ''Neurospora crassa''<br />
**[[2cya]] – ApTyrRS<br />
**[[1n3l]] - hTyrRS residues 1-364<br />
**[[1r6t]], [[1r6u]] – yTyrRS (mutant) <br />
**[[1jh3]] – GsTyrRS C-terminal – NMR<br />
*''Tyr-RS + small substrates or analogs''<br />
**[[3ts1]] – GsTyrRS + Tyr-adenylate intermediate<br />
**[[4ts1]] – GsTyrRS + Tyr<br />
**[[3p0h]], [[3p0i]], [[3p0j]] – LmTyrRS + inhibitor<br />
**[[3n2y]] – MjTyrRS + tetrazolyl phenylalanine<br />
**[[2zp1]] – MjTyrRS (mutant) + Tyr<br />
**[[1zh0]] - MjTyrRS (mutant) + naphthyl-Ala<br />
**[[1zh6]] - MjTyrRS (mutant) + acetyl-Phe<br />
**[[2ag6]] - MjTyrRS (mutant) + bromo-Phe<br />
**[[4hjx]] - MjTyrRS (mutant) + di-fluoro-Tyr<br />
**[[2yxn]] – EcTyrRS residues 1-322 + azido-Tyr<br />
**[[1vbm]] – EcTyrRS + Tyr-SA<br />
**[[1vbn]] – EcTyrRS (mutant) + Tyr-SA<br />
**[[1wq3]], [[1wq4]] - EcTyrRS (mutant) + Tyr<br />
**[[1x8x]] – EcTyrRS + Tyr<br />
**[[2pid]] – hTyrRS residues 28-375 + Tyr-SA<br />
**[[2j5b]] – TyrRS residues 2-346 + Tyr-ol – ''Acanthamoeba polyphaga'' minivirus<br />
**[[2dlc]] – yTyrRS + tRNA + Tyr-SA<br />
**[[2cyb]] – AfTyrRS + Tyr - ''Archaeoglobus fulgidus''<br />
**[[2cyc]] – PhTyrRS + Tyr<br />
**[[1q11]] – hTyrRS residues 1-364 + Tyr-ol<br />
**[[1h3e]] - TtTyrRS + Tyr-tRNA + Tyr-ol + ATP<br />
**[[1h3f]] - TtTyrRS + Tyr-ol<br />
**[[1jh3]] – GsTyrRS C-terminal – NMR<br />
**[[1jii]], [[ 1jij]], [[1jil]], [[1jik]] – SaTyrRS + inhibitor
*''Tyr-RS + tRNA''<br />
**[[1j1u]] – MjTyrRS + Tyr-tRNA
**[[2rkj]] – NcTyrRS + RNA
*'''Val-RS'''
**[[1iyw]] - TtValRS<br />
**[[1wk9]], [[ 1wka]] – TtValRS CP1 domain
*''Val-RS ternary complex''<br />
**[[1ivs]] – TtValRS + Val-SA + Val-tRNA<br />
**[[1gax]] - TtValRS + Val-adenylate analog + Val-tRNA
*'''Class II aaRS'''
*'''Ala-RS'''
**[[3g98]] – AaAlaRS residues 758-867<br />
**[[1riq]] - AaAlaRS catalytic fragment<br />
**[[2zze]], [[ 2zzf]], [[ 1wnu]], [[ 1wxo]], [[ 1v4p]] – PhAlaRS<br />
**[[2zvf]] – AfAlaRS C-terminal
*''Ala-RS + small substrates or analogs''<br />
**[[3hxu]], [[3hxv]], [[3hxw]] – EcAlaRS catalytic fragment + aa-adenylate <br />
**[[3hxz]], [[3hy0]], [[3hy1]] - EcAlaRS catalytic fragment (mutant) + aa-adenylate<br />
**[[3hxx]] - EcAlaRS catalytic fragment + AMPPCP<br />
**[[3hxy]] - EcAlaRS catalytic fragment + AMPPCP + Ala-AMP + PCP<br />
**[[3htz]] - AaAlaRS residues 2-454 + Ser<br />
**[[1yfr]] – AaAlaRS + ATP<br />
**[[1yfs]]  – AaAlaRS + Ala<br />
**[[1yft]], [[1ygb]] - AaAlaRS catalytic fragment + aa<br />
**[[2zzg]] - PhAlaRS + Ala-SA<br /
**[[2ztg]] – AfAlaRS + Ala-SA<br />
*'''Asp-RS'''
**[[3nen]], [[1b8a]] – TkAspRS - ''Thermococcus kodakarensis''<br />
**[[3i7f]] – EhAspRS<br />
**[[1wyd]] – AspRS – ''Sulfolobus tokodaii''<br />
**[[1eov]] - yAspRS<br />
**[[1n9w]], [[1l0w]], [[1g51]] – TtAspRS<br />
**[[1eqr]] – EcAspRS
*''Asp-RS + small substrates or analogs''<br />
**[[3nel]] – TkAspRS + Asp <br />
**[[3nem]] - TkAspRS + Asp-adenylate
*''Asp-RS + tRNA''<br />
**[[3kfu]], [[1efw]] – TtAspRS + tRNA <br />
**[[1asy]], [[1asz]] – yAspRS + Asp-tRNA
*''Asp-RS ternary complex''<br />
**[[1il2]], [[1c0a]] – EcAspRS + Asp-tRNA + Asp-adenylate
*'''Asn-RS'''
**[[1x56]] - PhAsnRS <br />
**[[2kqr]] – BmAsnRS N-terminal – NMR – ''Brugia malayi''
*''Asn-RS + small substrates or analogs''<br />
**[[2xti]] – BmAsnRS catalytic fragment + Asn-adenine analog<br />
**[[2xgt]] - BmAsnRS catalytic fragment + Asn-SA<br />
**[[1x54]] – PhAsnRS + Asn-adenylate<br />
**[[1x55]] - PhAsnRS + Asn-SA<br />
**[[11as]] – EcAsnRS + Asn<br />
**[[12as]] - EcAsnRS + Asn + AMP
*'''Gly-RS'''
**[[1ati]] – TtGlyRS<br />
**[[2q5h]] – hGlyRS residues 55-739<br />
**[[2q5i]] - hGlyRS residues 55-739 (mutant) <br />
**[[2pme]] – hGlyRS<br />
**[[2pmf]] – hGlyRS (mutant) <br />
**[[1j5w]] – TmGlyRS α chain
*''Gly-RS + small substrates or analogs''<br />
**[[2zt5]], [[ 2zxf]] – hGlyRS residues 55-739 + bis-adenosine tetraphosphate<br />
**[[2zt6]] - hGlyRS residues 55-739 + AMPCPP<br />
**[[2zt7]] - hGlyRS residues 55-739 + Gly + ATP<br />
**[[2zt8]] - hGlyRS residues 55-739 + Gly-AMP analog<br />
**[[1b76]] – TtGlyRS + ATP<br />
**[[1ggm]] – TtGlyRS + Gly-adenylate
*'''His-RS'''
**[[3net]] – HisRS – Nostoc<br />
**[[1h4v]] – TtHisRS<br />
**[[1qe0]] – SaHisRS<br />
**[[3hri]] – TbHisRS<br />
**[[1x59]] – hHisRS WHEP-TRS domain - NMR
*''His-RS + small substrates or analogs''<br />
**[[3lc0]] – HisRS residues 45-478 + His – ''Trypanosoma cruzi''<br />
**[[1adj]] – TtHisRS + His <br />
**[[3hrk]] - TbHisRS + His-adenylate<br />
**[[2el9]] - EcHisRS + His-SA<br />
**[[1kmm]], [[1ady]] - EcHisRS + His-adenylate<br />
**[[1kmn]] - EcHisRS + His-ol + ATP
*'''Phe-RS'''
**[[1pys]] – TtPheRS<br />
**[[3l4g]], [[ 3cmq]] – hPheRS<br />
**[[2cxi]] – PhPheRS β chain N-terminal<br />[[3ica]] – PheRS β chain – ''Porphyromonas gingivalis''
*''Phe-RS + small substrates or analogs''<br />
**[[3pco]] – EcPheRS + phenylalanine+ AMP<br />
**[[3hfz]], [[2amc]] – TtPheRS α+β chains + Tyr<br />
**[[2akw]], [[1b70]] - TtPheRS α+β chains + Phe<br />
**[[1jjc]], [[1b7y]] - TtPheRS α+β chains + Phe-adenylate<br />
**[[2aly]] - TtPheRS α+β chains + Phe-SA<br />
**[[2rhq]], [[2rhs]] – PheRS α+β chains (mutant) + inhibitor – ''Staphylococcus haemolyticus''
*''Phe-RS + tRNA''<br />
**[[1eiy]] - TtPheRS α+β chains + Phe-tRNA
*''Phe-RS ternary complex''
**[[2iy5]] - TtPheRS α+β chains + Phe-ol + Phe-tRNA
*'''Pro-RS'''
**[[1hc7]] – TtProRS<br />
**[[2i4l]] – RpProRS – ''Rhodopseudomonas palustris''<br />
**[[1nj2]] - MtProRS – ''Methanothermobacter thermautotrophicus''<br />
**[[1nj8]] – MjProRS<br />
**[[4k86]] – hProRS residues 1000-1512 <br />
*''Pro-RS + small substrates or analogs''<br />
**[[3ial]] – GlProRS residues 34-542 + Pro-adenylate<br />
**[[2i4m]], [[2i4n]] – RpProRS + aa-SA<br />
**[[2i4o]] – RpProRS + ATP<br />
**[[2j3l]] – EfProRS + Pro-SA – ''Enterococcus faecalis''<br />
**[[2j3m]] – EfProRS + Pro-ol + ATP<br />
**[[1nj1]], [[1nj5]], [[1nj6]] – MtProRS + aa-SA<br />
**[[1h4t]] - TtProRS + Pro
*''Pro-RS ternary complex''<br />
**[[1h4q]] - TtProRS + Pro-tRNA + Pro-ol<br />
**[[1h4s]] - TtProRS + Pro-tRNA + Pro-SA<br />
**[[5f9z]] – CpProRS residues 186-688 + halofuginone + AMPPNP <br />
**[[5f9y]] – CpProRS residues 186-688 + proline + AMP<br />
**[[4k87]] – hProRS residues 1000-1512 + proline + adenosine<br />
**[[4k88]] – hProRS residues 1000-1512 + halofunginone<br />
*Bifunctional RS (bifunctional glutamate/proline tRNA ligase)
**[[4hvc]] – hEPRS residues 1003-1513 + halofunginone + ATP analog<br />
**[[5v58]] – hEPRS residues 1003-1513 + AZ-SA<br />
**[[5vad]] – hEPRS residues 1003-1513 + inhibitor<br />
**[[5a1n]], [[5a34]], [[5a5h]] – hEPRS GST-like domain + EPRS-AIMP2<br />
*'''Pyrrolysyl-RS'''; domains – RNA-binding 1-101; catalytic 188-454
**[[2e3c]] - MmPylRS catalytic domain - ''Methanosarcina mazei''<br />
**[[3vqw]], [[3vqx]], [[4cs2]] - MmPylRS catalytic domain (mutant)<br />
**[[3dsq]] – DhPylRS <br />
*''Pyrrolysyl-RS binary complex''
**[[3qtc]] – MmPylRS catalytic domain (mutant) + AMP-ATP analog<br />
**[[2q7e]] - MmPylRS catalytic domain + ATP analog<br />
**[[2q7g]] - MmPylRS C-terminal+ pyrro-Lys analog+ ATP <br />
**[[3vqv]] - MmPylRS catalytic domain + AMPPNP <br />
**[[4bw9]], [[4cs4]], [[5k1p]], [[5k1x]] - MmPylRS catalytic domain (mutant) + AMPPNP <br />
**[[4bwa]] - MmPylRS catalytic domain (mutant) + adenylated norbornene <br />
**[[4ch3]], [[4ch4]], [[4ch5]], [[4ch6]] - MmPylRS catalytic domain + adenylated lysine derivative<br />
**[[4cs3]] - MmPylRS catalytic domain (mutant) + adenylated lysine derivative<br />
**[[5ud5]] - MmPylRS RNA-binding domain + Pyl-RNA<br />
**[[5v6x]] - MmPylRS RNA-binding domain (mutant) + Pyl-RNA<br />
**[[2zni]], [[2znj]] – DhPylRS + tRNA <br />
*''Pyrrolysyl-RS ternary complex''
**[[2zce]] - MmPylRS catalytic domain + pyrrolysine + ATP analog<br />
**[[2q7g]] - MmPylRS catalytic domain + pyrrolysine analog + ATP<br />
**[[2zim]], [[2q7h]] - MmPylRS catalytic domain + adenylated pyrrolysine + pyrophosphate<br />
**[[2zio]] - MmPylRS catalytic domain + AlocLys-AMP + ATP analog<br />
**[[3vqy]] - MmPylRS catalytic domain + butoxycarbonyl lysine + AMPPNP <br />
**[[4q6g]] - MmPylRS catalytic domain + acetyl lysine + ADPNP <br />
**[[4tqd]] - MmPylRS catalytic domain + iodo-Phe + ATP <br />
**[[4tqf]], [[4zib]] - MmPylRS catalytic domain + bromothienylo-Ala + ATP <br />
**[[2zin]] - MmPylRS catalytic domain + butoxycarbonyl lysine + ATP analog <br />
*'''Ser-RS'''
**[[3lsq]] – TbSerRS<br />
**[[1sry]] - TtSerRS<br />
**[[3err]] – TtSerRS/dynein heavy chain<br />
**[[2zr3]] – PhSerRS<br />
**[[2dq3]] – AaSerRS<br />
**[[2du7]] – MjSerRS<br />
**[[2odr]] – SerRS – ''Methanococcus maripaludis''<br />
**[[2cim]] – MbSerRS – ''Methanosarcina barkeri''<br />
**[[1wle]] – SerRS – bovine
*''Ser-RS + small substrates or analogs''<br />
**[[2zr2]] – PhSerRS + ATP<br />
**[[2cj9]] – MbSerRS + Ser-SA<br />
**[[2cjb]] – MbSerRS + Ser<br />
**[[2cja]] – MbSerRS + ATP<br />
**[[1ses]], [[1set]] – TtSerRS + Ser-adenylate analog<br />
**[[3lss]] – TbSerRS + ATP
*''Ser-RS + tRNA''<br />
**[[1ser]] – TtSerRS + Ser-tRNA<br />
**[[2du4]] - AfSerRS + Cys-tRNA
*''Ser-RS ternary complex''<br />
**[[2du3]] – AfSerRS + Cys-tRNA + phosphoserine<br />
**[[2du5]], [[2du6]] - AfSerRS (mutant) + Cys-tRNA + phosphoserine
*'''Thr-RS'''
**[[1y2q]] - PaThrRS editing domain<br />
**[[1wwt]] – hThrRS TGS domain – NMR<br />
**[[1tje]] - EcThrRS editing domain
*''Thr-RS + small substrates or analogs''<br />
**[[3pd2]], [[3pd3]], [[3pd4]], [[3pd5]] – PaThrRS editing domain + aa-aminoadenosine<br />
**[[2hkz]] – PaThrRS editing domain + Ser<br />
**[[2hl0]], [[2hl1]] - PaThrRS editing domain + Ser-adenylate<br />
**[[2hl2]] - PaThrRS editing domain + Ser-SA<br />
**[[1tke]] - EcThrRS editing domain + Ser<br />
**[[1tkg]] - EcThrRS editing domain + Ser-SA<br />
**[[1tky]] - EcThrRS editing domain + Ser-adenylate<br />
**[[1fyf]], [[1evl]] - EcThrRS catalytic and anticodon-binding domains + aa-SA<br />
**[[1evk]] - EcThrRS catalytic and anticodon-binding domains + Thr<br />
**[[1nyq]] – SaThrRS + Thr-SA<br />
**[[1nyr]] – SaThrRS + ATP
*''Thr-RS + tRNA''<br />
**[[1qf6]] – EcThrRS + Thr-tRNA<br />
**[[1kog]] – EcThrRS catalytic and anticodon-binding domains + mRNA
*Multifunctional RS
**[[1fyj]] – hRS - NMR
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Ann Taylor
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